Polybia-MP1 trifluoroacetate salt Chemical Properties

Boiling point:

1860.7±65.0 °C(Predicted)

Density 

1.227±0.06 g/cm3(Predicted)

solubility 

DMSO: Soluble: =10 mg/ml
Ethanol: Soluble: =10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml

pka

4.16±0.10(Predicted)

Sequence

H-Ile-Asp-Trp-Lys-Lys-Leu-Leu-Asp-Ala-Ala-Lys-Gln-Ile-Leu-NH2

Polybia-MP1 trifluoroacetate salt Usage And Synthesis

Uses

Polybia-MP1 is an antimicrobial mastoparan peptide[1].

References

[1] Marcia Perez dos Santos Cabrera, et al. Selectivity in the mechanism of action of antimicrobial mastoparan peptide Polybia-MP1. Eur Biophys J. 2008 Jul;37(6):879-91. DOI:10.1007/s00249-008-0299-7
[2] BIBIANA M. SOUZA . Structural and functional characterization of two novel peptide toxins isolated from the venom of the social wasp Polybia paulista[J]. Peptides, 2005, 26 11: Pages 2157-2164. DOI: 10.1016/j.peptides.2005.04.026
[3] ANNIELLE MENDES BRITO DA SILVA. Pro-necrotic Activity of Cationic Mastoparan Peptides in Human Glioblastoma Multiforme Cells Via Membranolytic Action.[J]. Molecular Neurobiology, 2018: 5490-5504. DOI: 10.1007/s12035-017-0782-1

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