Basic information Safety Supplier Related

Licochalcone E

Basic information Safety Supplier Related

Licochalcone E Basic information

Product Name:
Licochalcone E
Synonyms:
  • Licochalcone E
  • 2-Propen-1-one, 3-[5-[(1S)-1,2-dimethyl-2-propen-1-yl]-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2E)-
CAS:
864232-34-8
MF:
C21H22O4
MW:
338.4
Mol File:
864232-34-8.mol
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Licochalcone E Chemical Properties

storage temp. 
4°C, protect from light
solubility 
DMSO: 125 mg/mL (369.39 mM)
form 
Solid
color 
Yellow to orange
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Licochalcone E Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the rhizome of Glycyrrhiza uralensis Fisch.

Uses

Licochalcone E, a flavonoid compound isolated from Glycyrrhiza uralensis, inhibits NF-κB and AP-1 transcriptional activity through the inhibition of AKT and MAPK activation[1].

Biological Activity

Licochalcone E, a flavonoid extracted from Glycyrrhiza inflate, inhibits the transcriptional activity of NF-κB and AP-1 by inhibiting the activation of AKT and MAPK.

target

AKT, MAPK, NF-κB.

References

[1] Lee HN, et al. Mechanisms by which licochalcone e exhibits potent anti-inflammatory properties: studies with phorbol ester-treated mouse skin and lipopolysaccharide-stimulated murine macrophages. Int J Mol Sci. 2013 May 24;14(6):10926-43. DOI:10.3390/ijms140610926

Licochalcone ESupplier

Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Email
2355253622@qq.com;
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Email
aileen@chemfaces.com
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Email
3008007409@qq.com
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Email
psaitong@jm-bio.com