N3-PEG12-CH2CH2COOH Chemical Properties

storage temp. 

Storage temp. 2-8°C

form 

Oil

color 

White to off-white

Safety Information

HS Code 

2918999090

N3-PEG12-CH2CH2COOH Usage And Synthesis

Uses

Azido-PEG12-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG12-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N3-PEG12-CH2CH2COOH(2152679-71-3)Related Product Information

• Azido-PEG12-Br
• Azido-PEG12-NHS ester
• Azide-PEG12-Tos
• N3-PEG12-OH
• N3-PEG12-Hydrazide
• Azido-PEG12-NHBoc
• Azido-PEG12-Amine
• Azido-PEG12-t-butyl ester
• N3-PEG12-N3
• N3-PEG7-OH
• Azido-PEG12-acid
• Azido-PEG1-PFP ester
• N3-PEG6-CH2COOH
• Azido-PEG12-NHS ester
• Azido-PEG12-NHS ester
• Azido-PEG5-acid
• Azido-PEG1-acid