5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID Chemical Properties

Melting point:

-49 °C(lit.)

Boiling point:

169-171 ;°C/0.15 ;mmHg(lit. )

Density 

0.945 g/mL at 25 °C

Flash point:

-16 °C

storage temp. 

-20°C

solubility 

0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible

form 

methyl acetate solution

Stability:

Light Sensitive, Temperature Sensitive

Safety Information

Hazard Codes 

F,Xi

Risk Statements 

11-36-66-67-19

Safety Statements 

16-26-29-33

RIDADR 

UN 1231 3/PG 2

WGK Germany 

1

MSDS

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5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID Usage And Synthesis

Description

Arachidonic acid-d₈ contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of arachidonic acid by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Receptor-stimulated release, metabolism, and re-uptake of free arachidonate are all important aspects of cell signaling and inflammation.

Uses

Arachidonic Acid-d8 is the deuterated form of Arachidonic Acid (A765000), which is an essential fatty acid and a precursor in biosynthesis of prostaglandins, thromboxanes, and leukotrienes. Arachidonic Acid occurs in the liver, brain, glandular organs, and depot fats of animals, in small amounts in human depot fats, and it is also a constituent of animal phosphatides.

5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID(69254-37-1)Related Product Information

• Methyl acetate
• 5S-HYDROXY-6E,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID
• Arachidonic acid
• 5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID
• CIS-ETHYLENE-1,2-D2
• 5Z,8Z,11Z,14Z-EICOSATETRAENOIC-5,6,8,9,11,12,14,15-D8 ACID, 2-GLYCERYL ESTER
• ARACHIDONYL ALCOHOL APPROX 99
• PROPENE-2-D1
• ETHYLENE-D1
• PROPENE-1-D1