2-Methylbenzoxazole Chemical Properties

Melting point:

5-10 °C(lit.)

Boiling point:

178 °C(lit.)

Density 

1.121 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.548(lit.)

FEMA 

4398 | 2-METHYL-4,5-BENZOXAZOLE

Flash point:

167 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

1.58±0.10(Predicted)

form 

clear liquid

Specific Gravity

1.121

color 

Colorless to Light yellow to Light orange

Odor

at 0.10 % in dipropylene glycol. tobacco burnt phenolic meaty powdery capers

Odor Type

tobacco

Water Solubility 

Not miscible in water.

JECFA Number

1557

BRN 

112297

InChIKey

BJEBCCKIVRWKGV-UHFFFAOYSA-N

LogP

1.82

CAS DataBase Reference

95-21-6(CAS DataBase Reference)

NIST Chemistry Reference

Benzoxazole, 2-methyl-(95-21-6)

EPA Substance Registry System

Benzoxazole, 2-methyl- (95-21-6)

Safety Information

Hazard Codes 

Xn,Xi,C

Risk Statements 

22-36/37/38-41-37/38-34-20/21/22

Safety Statements 

26-36/37/39-37/39-45-27

RIDADR 

UN 1760

WGK Germany 

3

RTECS 

DM4850000

F 

8

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29349990

MSDS

• Language:English Provider:2-Methylbenzoxazole
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2-Methylbenzoxazole Usage And Synthesis

Chemical Properties

clear colourless to yellow liquid

Chemical Properties

Yellowish liquid, solidifying in the cold.
Insoluble in water, soluble in alcohol, miscible with most oils. Very sweet odor of rather gassy-pungent character when undiluted, becoming floralsweet, heavy, when diluted.

Uses

2-Methylbenzoxazole has been used in synthesis of bis-styryl dyes. It is also used in medicine and for the synthesis of other organic compounds.

Production Methods

2-Methylbenzoxazole can be produced from ortho-Aminophenol plus Acetic anhydride by heating and distilling.

Definition

ChEBI: A member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole substituted by a methyl group at position 2.

Aroma threshold values

High strength odor, tobacco type; recommend smelling in a 0.10% solution or less.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 675, 1996 DOI: 10.1016/0040-4039(95)02240-6

Biochem/physiol Actions

Odor at 1.0%: Musty, nutty pecan, almond and pistachio-like, tobacco, vanilla-like with brown roasted burnt rubber and cooked rice-like nuances.Taste at 2.0ppm: Musty, nutty, vanilla and rice-like.

2-Methylbenzoxazole(95-21-6)Related Product Information

• Tolyltriazole
• 1H-Benzotriazole
• Difenoconazole
• Albendazole
• 2,1,3-Benzothiadiazole
• 2-Phenylbenzoxazole
• 2,5-Dimethylbenzoxazole
• 2-METHYLNAPHTHO(2,1-D)OXAZOLE
• 5-CHLORO-2-METHYLBENZOXAZOLE,5-CHLORO-2-METHYLBENZOXAZOLE 98+%,Chloro-2-methylbenzoxazole
• 3,3'-DIETHYLOXADICARBOCYANINE IODIDE
• 5-Methyl-1H-benzotriazole
• 2-(2-HYDROXYPHENYL)BENZOXAZOLE
• 2,5,6-TRIMETHYLBENZOXAZOLE
• 2,2'-(1,2-Ethenediyldi-4,1-phenylene)bisbenzoxazole
• 2-Chloro-3-ethylbenzoxazolium tetrafluoroborate
• BBOT
• 2-(4-BIPHENYLYL)-6-PHENYLBENZOXAZOLE
• 2-Methyl-5-phenylbenzoxazole