BROMPERIDOL
BROMPERIDOL Basic information
- Product Name:
- BROMPERIDOL
- Synonyms:
-
- R 11333
- 4-(4-(4-bromophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanon
- 4-(4-(4-bromophenyl)-4-hydroxypiperidino)-4’-fluorobutyrophenone
- 4-(4-(p-bromophenyl)-4-hydroxypiperidino)-4’-fluoro-butyrophenon
- 4-(4-(p-bromophenyl)-4-hydroxypiperidino)-4’-fluorobutyrophenone
- 4-(4-(p-bromophenyl)-4-hydroxypiperidinol)-4’-fluorobutyrophenone
- bromoperidol
- 4-[4-(4-BROMOPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE
- CAS:
- 10457-90-6
- MF:
- C21H23BrFNO2
- MW:
- 420.32
- EINECS:
- 233-943-3
- Product Categories:
-
- XEFO
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 10457-90-6.mol
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BROMPERIDOL Chemical Properties
- Melting point:
- 156-158°C
- Boiling point:
- 215.2°C (rough estimate)
- Density
- 1.3109 (estimate)
- storage temp.
- Refrigerator
- solubility
- H2O: insoluble
- pka
- 8.6-8.7(at 25℃)
- form
- solid
- color
- white
- CAS DataBase Reference
- 10457-90-6(CAS DataBase Reference)
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MSDS
- Language:English Provider:SigmaAldrich
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BROMPERIDOL Usage And Synthesis
Chemical Properties
Tan Solid
Uses
Bromine analog of Haloperidol. Antipsychotic
Uses
analgesic, antiinflammatory
Definition
ChEBI: Bromperidol is an aromatic ketone.
Biological Activity
Butyrophenone antipsychotic; D2 dopamine and 5-HT2A serotonin antagonist.
in vivo
Bromperidol antagonises stereotyped behaviour and agitation induced by apomorphine or amphetamine, and inhibits conditioned reactions and learned intracranial self-stimulation in rats[1].
Bromperidol antagonises apomorphine-induced emesis and inhibits the conditioned avoidance response in dogs[1].
IC 50
D2 Receptor
BROMPERIDOLSupplier
J & K SCIENTIFIC LTD.
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- 18210857532; 18210857532
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- +86 (0) 571 85 58 67 18
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- 021-50135380
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- 1-631-485-4226; 16314854226
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BROMPERIDOL(10457-90-6)Related Product Information
- Thioridazine hydrochloride
- HALOPERIDOL DECANOATE
- trimetozine
- Fluphenazine decanoate
- BROMPERIDOL DECANOATE
- Bromperidol-d4
- 4-bromo-alpha-ethylbenzyl alcohol
- (R)-4-Bromo-alpha-methylbenzyl alcohol
- 4-phenyl-1-(4-phenylbutyl)piperidine
- 4-(4-Bromophenyl)-4-piperidinol
- 1-(4-Bromophenyl)ethanol
- 4-(4'-Bromophenyl)piperidine
- (S)-4-Bromo-alpha-methylbenzyl alcohol
- BROMPERIDOL
- (R)-1-(4-BROMOPHENYL)-1-PROPANOL