2-Benzyloxyethanol Chemical Properties

Melting point:

<-75 °C

Boiling point:

265 °C (lit.)

Density 

1.071 g/mL at 25 °C (lit.)

vapor pressure 

7.3hPa at 25℃

refractive index 

n20/D 1.521(lit.)

Flash point:

110 °C

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

14.40±0.10(Predicted)

form 

Liquid

color 

Clear colorless

Specific Gravity

1.07

Odor

mild rose

Water Solubility 

4.282g/L(23 ºC)

BRN 

2043566

InChIKey

CUZKCNWZBXLAJX-UHFFFAOYSA-N

LogP

1.01 at 25℃

CAS DataBase Reference

622-08-2(CAS DataBase Reference)

NIST Chemistry Reference

Ethanol, 2-(phenylmethoxy)-(622-08-2)

EPA Substance Registry System

Ethanol, 2-(phenylmethoxy)- (622-08-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

RTECS 

KJ7550000

HS Code 

29052900

Hazardous Substances Data

622-08-2(Hazardous Substances Data)

MSDS

• Language:English Provider:Glycol benzyl ether
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

2-Benzyloxyethanol Usage And Synthesis

Description

Benzyl-PEG2-alcohol is a PEG linker with an acid labile, benzyl protecting group and a reactive primary alcohol. The primary alcohol can react and further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Chemical Properties

Ethylene glycol monobenzyl ether is a Colorless to light yellow liquid which will dissolve a large number of organic substances among which are oils, fats, greases, some vinyl resins, dewaxed damar, rosin, ester gum, etc. It is used principally as a high boiling solvent in lacquers, inks, and textile dyeing.

Uses

2-Benzyloxyethanol is used in a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols.

Uses

2-(Benzyloxy)ethanol has been used in:

• 9-(2-hydroxyethyl)-linked synthesis of 2,6-diaminopurines
• synthesis of benzyloxy ethyl methacrylate monomer by esterification with methacryloyl chloride
• a base-free iridium-catalyzed direct alkylation of active methylene compounds with alcohols

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 389, 1990 DOI: 10.1016/S0040-4039(00)94562-3

Hazard

Toxic by ingestion.

2-Benzyloxyethanol(622-08-2)Related Product Information

• p-Anisidine
• Anisole
• 3-(METHOXYMETHOXY)BENZALDEHYDE
• 2-Methoxyethanol
• Diethylene glycol
• Ethylene glycol diacetate
• Ethylene glycol
• 2-Phenoxyethanol
• Benzyl alcohol
• ETHYLENE OXIDE
• Ethanol
• p-Anisaldehyde
• Monoethanolamine
• Diethylene glycol monobutyl ether
• 4-Methoxybenzylchloride
• ETHYLENE
• 2-Butoxyethanol
• (Trifluoromethoxy)benzene