2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Basic information
- Product Name:
- 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid
- Synonyms:
-
- Uvistat 1121
- UV ABSORBER HMBS
- 5-BENZOYL-4-HYDROXY-2-METHOXYBENZENESULFONIC ACID
- TIMTEC-BB SBB002961
- SULISOBENZONE
- spectra-sorb uv 284
- 2-HYDROXY-4-METHOXYBENZOPHENONE-5-SULPHONIC ACID
- Uv absorber BP-4(UV-284)
- CAS:
- 4065-45-6
- MF:
- C14H12O6S
- MW:
- 308.31
- EINECS:
- 223-772-2
- Product Categories:
-
- Organic acids
- Industrial/Fine Chemicals
- Aromatic Benzophenones & Derivatives (substituted)
- Building Blocks
- Chemical Synthesis
- SUNGARD
- Organic Building Blocks
- Sulfonic/Sulfinic Acids
- Sulfur Compounds
- 4065-45-6
- Mol File:
- 4065-45-6.mol
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Chemical Properties
- Melting point:
- 170 °C
- Boiling point:
- 0°C
- Density
- 1.4574 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.5300 (estimate)
- Flash point:
- 0°C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- -0.70±0.50(Predicted)
- color
- White to Off-White
- Water Solubility
- 300.92g/L at 25℃
- Merck
- 14,8983
- BRN
- 2889165
- InChIKey
- CXVGEDCSTKKODG-UHFFFAOYSA-N
- LogP
- 0.515 at 25℃
- CAS DataBase Reference
- 4065-45-6(CAS DataBase Reference)
- EPA Substance Registry System
- Sulisobenzone (4065-45-6)
Safety Information
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-37/39-36/37/39-27
- WGK Germany
- 1
- RTECS
- DB5044300
- TSCA
- Yes
- HS Code
- 29147000
- Hazardous Substances Data
- 4065-45-6(Hazardous Substances Data)
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Usage And Synthesis
Chemical Properties
white to yellowish powder
Originator
Uval,Dome,US,1965
Uses
sulisobenzone is the drug name for benzophenone-4, a sunscreen chemical.
Uses
ultraviolet screen
Uses
Ultraviolet absorber for leather and textile fibers; in cosmetics and shampoos.
Uses
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid is a commonly used, FDA approved sunscreen chemical with uVA-absorbing properties and an approved usage level of 5 to 10 percent. It protects a formulation from the effects of uV-light exposure.
Definition
ChEBI: Sulisobenzone is a member of benzophenones.
Manufacturing Process
663 g of dichloroethane and 74.6 g 2-hydroxy-4-methoxybenzophenone were charged into a 3-neck flask equipped with stirrer, thermometer, reflux condenser and dropping funnel and a heating mantle. The solution was heated to the reflux temperature (85°C to 86°C) and was dehydrated by distilling off 66.5 g 1,2-dichloroethane. While maintaining at reflux, 30 g chlorosulfonic acid was added slowly over a period of about two hours. The rate of addition was regulated by the speed of evolution of the HCl. After all the chlorosulfonic acid was added, the charge was still maintained at reflux for an additional 15 minutes to remove traces of HCl. It was then cooled to 5°C and filtered. The filter cake was washed with 500 g cold 1,2-dichloroethane and dried. 98 g of product were obtained.
brand name
Sungard (Bayer).
Therapeutic Function
Sunscreen agent
General Description
Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.
Flammability and Explosibility
Non flammable
Contact allergens
BZP-4 is widely used in cosmetics, particularly shampoos and hair products. Cross-reactivity is rarely expected in patients photoallergic to ketoprofen.
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Preparation Products And Raw materials
Raw materials
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2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid(4065-45-6)Related Product Information
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