QUININIC ACID Chemical Properties

Melting point:

280°C (decompose)

Boiling point:

341.49°C (rough estimate)

Density 

1.2621 (rough estimate)

refractive index 

1.4950 (estimate)

storage temp. 

2-8°C

solubility 

Solubility Slightly soluble in water, cold ethanol, ether

pka

5.53(at 25℃)

form 

crystals

color 

Pale yellow

PH Range

Yellow I uorescent (4.0) to blue I uorescent (5.0)

Merck 

14,8062

Major Application

Display device, antihypertensive food materials, nucleic acids, antimalarial agent, antimalerial agent

CAS DataBase Reference

86-68-0

Safety Information

HS Code 

2933.49.7000

QUININIC ACID Usage And Synthesis

Description

6-Methoxy-4-quinolinecarboxylic Acid is a derivative of 4-quinolinecarboxylic acids, which is a potential antitumor (such as leukemia) and antiviral agent. It also has the potential to be used as immunosuppressive reagent as well as for the treatment of skin and epithelial diseases.

Sources

https://www.sigmaaldrich.com/catalog/product/aldrich/174823?lang=en&region=US
https://link.springer.com/article/10.1007/s11094-009-0187-1
https://patents.google.com/patent/US5084462A/en
https://patents.google.com/patent/US4861783A/en

Uses

6-methoxyquinoline-4-carboxylic Acid is used in the preparation of tetrahydroisoquinoline amides as multidrug resistance reversers.

Synthesis Reference(s)

The Journal of Organic Chemistry, 11, p. 803, 1946 DOI: 10.1021/jo01176a024

QUININIC ACID(86-68-0)Related Product Information

• QUININIC ACID
• 4-METHOXY-2-QUINOLINECARBOXYLIC ACID
• 2-HYDROXY-6-METHOXY-QUINOLINE-4-CARBOXYLIC ACID
• 6-METHOXY-2-PHENYL-4-QUINOLINECARBOXYLIC ACID
• 2-(4-BROMO-PHENYL)-6-METHOXY-QUINOLINE-4-CARBOXYLIC ACID
• 2,3,7,8-TETRAHYDRO-1H-6,9-DIOXA-4-AZA-CYCLOPENTA[B]ANTHRACENE-11-CARBOXYLIC ACID
• 6-METHOXYCINCHONINE ACID SULFATE
• 2-(4-HYDROXY-3-METHOXY-PHENYL)-5,6,7-TRIMETHOXY-QUINOLINE-4-CARBOXYLIC ACID
• AKOS AU36-M123
• 7-CYCLOPROPYL-2,3-DIHYDRO[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-PYRIDIN-3-YL-2,3-DIHYDRO[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-THIEN-2-YL-2,3-DIHYDRO[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-BENZO[1,3]DIOXOL-5-YL-2,3-DIHYDRO-[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• AKOS BB-8995
• 7-(4-HYDROXY-3-METHOXY-PHENYL)-2,3-DIHYDRO-[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-METHYL-2,3-DIHYDRO[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-(3,4,5-TRIMETHOXY-PHENYL)-2,3-DIHYDRO-[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID
• 7-(4-METHOXYCARBONYL-PHENYL)-2,3-DIHYDRO-[1,4]DIOXINO[2,3-G]QUINOLINE-9-CARBOXYLIC ACID