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N-(2-Hydroxyethyl)succinimide

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N-(2-Hydroxyethyl)succinimide Basic information

Product Name:
N-(2-Hydroxyethyl)succinimide
Synonyms:
  • 2,5-Pyrrolidinedione,1-(2-hydroxyethyl)-
  • 1-(2-hydroxyethyl)-2,5-Pyrrolidinedione
  • 1-(2-Hydroxyethyl)
  • N-(2-HYDROXYETHYL)SUCCINIMIDE
  • 1-(2-HYDROXY-ETHYL)-PYRROLIDINE-2,5-DIONE
  • N-(2-N-(2-Hydroxyethyl)succinimide
  • Diroximel Fumarate Impurity 1
  • RSYY(Donepezil Hydrochloride)-3
CAS:
18190-44-8
MF:
C6H9NO3
MW:
143.14
Product Categories:
  • Carbonyl Compounds
  • Cyclic Imides
  • Organic Building Blocks
Mol File:
18190-44-8.mol
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N-(2-Hydroxyethyl)succinimide Chemical Properties

Melting point:
57-61 °C (lit.)
Boiling point:
160-164 °C/3 mmHg (lit.)
Density 
1.3075 (rough estimate)
refractive index 
1.4290 (estimate)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Chloroform (Sparingly)
form 
Solid
pka
14.20±0.10(Predicted)
color 
White to Off-White
BRN 
124744
InChI
InChI=1S/C6H9NO3/c8-4-3-7-5(9)1-2-6(7)10/h8H,1-4H2
InChIKey
TWYIPMITVXPNEM-UHFFFAOYSA-N
SMILES
N1(CCO)C(=O)CCC1=O
CAS DataBase Reference
18190-44-8
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
2933998090

MSDS

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N-(2-Hydroxyethyl)succinimide Usage And Synthesis

Synthesis

Succinimide (500 g; 5.0 mol), ethylene carbonate (444.34 g; 5.0 mol) and sodium carbonate (26.74 g; 0.25 mol) were mixed and slowly heated to 130C under stirring for 7 hours. The product was distilled via vacuum to yield N-(2-Hydroxyethyl)succinimide as a colourless substance.

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