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2-Mercapto-5-methyl-1,3,4-thiadiazole

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2-Mercapto-5-methyl-1,3,4-thiadiazole Basic information

Product Name:
2-Mercapto-5-methyl-1,3,4-thiadiazole
Synonyms:
  • 2,3-Dihydro-5-methyl-1,3,4-thiadiazole-2-thione
  • 2-Methyl-1,3,4-thiadiazole-5(4H)-thione
  • MMTD 2-Methyl-5-mercapto-1,3,4-thiadiazole
  • 2-Mercapto-5-Methyl-1
  • MMTD)2-Mercapto-5-Methyl-1
  • Cefazolin IMpurity E
  • 2-Mercapto-5-methyl-1,3,4-thiadiazole, 5-Methyl-1,3,4-thiadiazole-2-thiol
  • 2-Methyl-5-thio-1,3,4-thiadiazole
CAS:
29490-19-5
MF:
C3H4N2S2
MW:
132.21
EINECS:
249-667-1
Product Categories:
  • chemical additive
  • pharmaceutical intermediate
  • THIOL
  • API intermediates
  • Cephalosporins
Mol File:
29490-19-5.mol
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2-Mercapto-5-methyl-1,3,4-thiadiazole Chemical Properties

Melting point:
185-188 °C
Boiling point:
182.9±23.0 °C(Predicted)
Density 
1.373 (estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
chloroform: soluble10mg/mL, clear to very slightly hazy, colorless
form 
solid
pka
6.49±0.40(Predicted)
color 
White to Off-White
Water Solubility 
2 g/100 mL
BRN 
606663
CAS DataBase Reference
29490-19-5(CAS DataBase Reference)
NIST Chemistry Reference
1,3,4-Thiadiazole-2(3H)-thione, 5-methyl-(29490-19-5)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29349990

MSDS

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2-Mercapto-5-methyl-1,3,4-thiadiazole Usage And Synthesis

Chemical Properties

white crystal powder

Uses

thiadiazole pharmaceutical intermediate

Uses

5-Methyl-1,3,4-thiadiazol-2-thiol (Cefazolin EP Impurity E), is a new potent nitrification inhibitors. It is also an intermediate in the synthesis of Thiazolylacetylglycine Oxime (T344230).

General Description

5-Methyl-1,3,4-thiadiazole-2-thiol is a pharmaceutical intermediate. UV and UV/H2O2 induced degradation of 5-methyl-1,3,4-thiadiazole-2-thiol has been investigated.

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