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Hematoxylin

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Hematoxylin Basic information

Product Name:
Hematoxylin
Synonyms:
  • GILL 2 METHOD HEMATOXYLIN STAIN
  • GILL HEMATOXYLIN SOLUTION NO II
  • GILL'S HEMATOXYLIN NO 2
  • GILL'S HEMATOXYLIN SOLUTION NO 2
  • GILLS II HAEMATOXYLIN
  • HEMATOXYLIN STAIN, GILL 2
  • HEMATOXYLIN SOLUTION GILL NO 2
  • HEMATOXYLIN, GILL II
CAS:
517-28-2
MF:
C16H14O6
MW:
302.28
EINECS:
208-237-3
Product Categories:
  • Polymethine
  • Flavone
  • Cytology StainsHematology and Histology
  • marker
  • Inhibitors
  • Miscellaneous
  • Colours, Dyes, Indicators & Pigments
  • Hematology and Histology
  • Routine Histology Stains
Mol File:
517-28-2.mol
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Hematoxylin Chemical Properties

Melting point:
200 °C (dec.)(lit.)
Boiling point:
363.32°C (rough estimate)
Density 
1.2514 (rough estimate)
vapor pressure 
0-0Pa at 20-25℃
refractive index 
1.4600 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Soluble in 95% ethanol(1 mg/mL).
Colour Index 
75290
pka
6.7(at 25℃)
form 
Powder/Solid
color 
Yellow to Brown
PH Range
Red (0.0) to yellow (1.0);Pale yellow (5.0) to violet (6.0)
Water Solubility 
SOLUBLE IN HOT WATER
Sensitive 
Light Sensitive
λmax
292nm, 445nm, 560nm
Merck 
14,4637
BRN 
91399
Stability:
Stable, but may discolour on exposure to light. Incompatible with strong oxidizing agents.
Major Application
Plasma displays, textiles, hair dyes, identifying fresh and stale rice, diag-nosing cancer progression, detecting nosing cancer progression, cervical disease, central nervous system malfunctions, detecting genes, breast cancer, collagen in a tissue sample, apoptosis, demyelinating diseases, antigens, treatment of age-related macular degeneration, burns, prostate cancer, diabetesand obesity, viral diseases, neoplasms, peripheral neural and vascular ailments, skin disorders, biotechnological applications, reference standard materials for cytology, histology andimmunohistochemistry
InChIKey
WZUVPPKBWHMQCE-UHFFFAOYSA-N
LogP
0.3 at 30℃ and pH6.9
CAS DataBase Reference
517-28-2
EPA Substance Registry System
Hematoxylin (517-28-2)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
MH7875000
TSCA 
Yes
HS Code 
32030019
Hazardous Substances Data
517-28-2(Hazardous Substances Data)

MSDS

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Hematoxylin Usage And Synthesis

Chemical Properties

light brown crystals or powder

Uses

Colorant in inks, biological stains.

Uses

Hematoxylin and eosin together make up Hematoxylin and eosin stain, one of the most commonly used stains in histology. Metal-haematein complexes are used to stain cell nuclei prior to examination under a microscope. Structures that stain with iron- or aluminum-haematein are often called basophilic, even though the mechanism of the staining is different from that of staining with basic dyes.

Definition

ChEBI: (+)-haematoxylin is a haematoxylin. It is an enantiomer of a (-)-haematoxylin.

General Description

White to yellowish crystals that redden on exposure to light.

Air & Water Reactions

Soluble in hot water, slightly water soluble in cold .

Reactivity Profile

Sensitive to light. .

Hazard

May be carcinogenic.

storage

Store at RT

Purification Methods

Hematoxylin recrystallises from H2O (as trihydrate) in white-yellow crystals which become red on exposure to light and then melt at 100-120o. It has been recrystallised from Me2CO/*C6H6. It has been recrystallised as well from dilute aqueous NaHSO3 until colourless and is soluble in alkali, borax and glycerol. Store it in the dark below 0o. [Morsingh & Robinson Tetrahedron 26 182 1970, Dann & Hofmann Chem Ber 98 1498 1955, Beilstein 17/8 V 469.]

Hematoxylin Preparation Products And Raw materials

Raw materials

HematoxylinSupplier

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0731-85561035 13319583233
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