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4,4-Bis(diethylphosphonomethyl)biphenyl

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4,4-Bis(diethylphosphonomethyl)biphenyl Basic information

Product Name:
4,4-Bis(diethylphosphonomethyl)biphenyl
Synonyms:
  • Biphenyl-benzyl ester
  • TETRAETHYL [4,4'-BIPHENYLYLENEBIS(METHYLENE)]BISPHOSPHONATE
  • TETRAETHYL (4,4'-BIPHENYLYLENEDIMETHYLENE)DIPHOSPHONATE
  • 4,4'-Bis(diethylphosphono methy)biphenyl
  • [4,4'-Biphenylylenebis(methylene)]bisphosphonic Acid Tetraethyl Ester Tetraethyl [4,4'-Biphenylylenebis(methylene)]bisphosphonate
  • [4,4'-BIPHENYLYLENEBIS(METHYLENE)]BISPHOSPHONIC ACID TETRAETHYL ESTER
  • 4,4'-BIS[(DIETHOXYPHOSPHINYL)METHYL]BIPHENYL
  • 4,4'-BIS(DIETHOXYPHOSPHOMETHYL)-1,1'-BIPHENYL
CAS:
17919-34-5
MF:
C22H32O6P2
MW:
454.43
Product Categories:
  • Synthetic Organic Chemistry
  • Wittig & Horner-Emmons Reaction
  • Biphenyl & Diphenyl ether
  • Horner-Emmons Reaction
Mol File:
17919-34-5.mol
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4,4-Bis(diethylphosphonomethyl)biphenyl Chemical Properties

Melting point:
108-110°C
Boiling point:
578.4±50.0 °C(Predicted)
Density 
1.155±0.06 g/cm3(Predicted)
form 
powder to crystal
color 
White to Almost white
InChIKey
DRCOGQJUVZRNSQ-UHFFFAOYSA-N
CAS DataBase Reference
17919-34-5(CAS DataBase Reference)
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Safety Information

HS Code 
2931.90.6000
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4,4-Bis(diethylphosphonomethyl)biphenyl Usage And Synthesis

Uses

4,4-Bis(diethylphosphonomethyl)biphenyl is a white powder used as an organic synthesis intermediate for the synthesis of fluorescent brighteners CBS-X, CBS-127, etc.

Synthesis

A mixture of 4,4’-bis(bromoethyl)biphenyl (0.204 g, 0.592 mmol) and P(OEt)3 (1 mL, 6.27mmol) was heated at 150°C for 12 h under N2. The mixture was purified over silica gel column chromatography using ethyl acetate as eluant, giving 258 mg of 4,4-Bis(diethylphosphonomethyl)biphenyl. Yield: 96 percent.

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