2-Bromo-4-(trifluoromethyl)pyridine Chemical Properties

Melting point:

-21--20 °C

Boiling point:

84-85 °C/14 mmHg

Density 

1.827 g/mL at 25 °C

refractive index 

n20/D 1.478

Flash point:

164 °F

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

form 

clear liquid

pka

-1.57±0.10(Predicted)

color 

Colorless to Light yellow to Light orange

InChIKey

WZVHLUMAQLUNTJ-UHFFFAOYSA-N

CAS DataBase Reference

175205-81-9(CAS DataBase Reference)

Safety Information

Hazard Codes 

T,Xi

Risk Statements 

25-36/37/38-37/38-36

Safety Statements 

26-36/37-45-37

RIDADR 

UN 2810 6.1/PG 3

WGK Germany 

3

Hazard Note 

Toxic/Irritant

HazardClass 

IRRITANT

PackingGroup 

Ⅲ

HS Code 

2933399990

MSDS

• Language:English Provider:SigmaAldrich

2-Bromo-4-(trifluoromethyl)pyridine Usage And Synthesis

Uses

Regioselective deprotonation at C-3 with LDA followed by trapping with carbon dioxide provides the correspondin nicotinic acid.

Uses

2-Bromo-4-(trifluoromethyl)pyridine in used in the preparation of pyrazolopyridines as kinase LRRK2 inhibitors for treating and preventing cancer and neurodegenerative diseases.

2-Bromo-4-(trifluoromethyl)pyridine(175205-81-9)Related Product Information

• 4-(Trifluoromethyl)pyridine
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