Basic information Safety Supplier Related
ChemicalBook >  Product Catalog >  API >  Anesthetic Agents >  Local anesthetics >  Bupivacaine hydrochloride

Bupivacaine hydrochloride

Basic information Safety Supplier Related

Bupivacaine hydrochloride Basic information

Product Name:
Bupivacaine hydrochloride
Synonyms:
  • BUPIVACAINE HYDROCHLORIDE
  • (+,-)-1-butyl-2’,6’-pipecoloxylididemonohydrochloride,monohydrate
  • Bupivacaine hydrochloride 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide hydrochloride
  • Bupivacaine Hydrochloride, USP
  • IN STOCK BUPIVACAINE HYDROCHLORIDE CAS NO.14252-80-3
  • BUPIVACAINE HYDROCHLORIDE CAS NO.14252-80-3
  • Local Anesthetic Pharmaceutical Raw Material Bupivacaine HCl CAS 14252-80-3
  • 1-butyl-2’,6’-pipecoloxylididehydrochloride(+-)
CAS:
14252-80-3
MF:
C18H28N2O.ClH
MW:
324.89
EINECS:
627-065-3
Product Categories:
  • Sodium channel
  • Amines
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API
  • TAXOL
Mol File:
14252-80-3.mol
More
Less

Bupivacaine hydrochloride Chemical Properties

Melting point:
249-2510C
storage temp. 
Refrigerator
solubility 
Soluble in water, freely soluble in alcohol.
CAS DataBase Reference
14252-80-3(CAS DataBase Reference)
More
Less

Safety Information

Hazard Codes 
T+
Risk Statements 
26/27/28
Safety Statements 
22-36/37/39-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
TK6125000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933399090
Toxicity
LD50 in mice (mg/kg): 7.8 i.v., 82 s.c. (Henn, Brattsand)
More
Less

Bupivacaine hydrochloride Usage And Synthesis

Chemical Properties

White Solid

Uses

antineoplastic

Uses

Sodium channel blocker, local anesthetic

brand name

Marcaine (Hospira); Sensorcaine (AstraZeneca).

Biological Functions

Bupivacaine hydrochloride (Marcaine, Sensorcaine) has particularly long action, and some nerve blocks last more than 24 hours; this is often an advantage for postoperative analgesia. Its use for epidural anesthesia in obstetrics has attracted interest because it can relieve the pain of labor at concentrations as low as 0.125% while permitting some motor activity of abdominal muscles to aid in expelling the fetus. The lower concentration minimizes the possibility of cardiac toxicity. Fetal drug concentrations remain low, and drug-induced neurobehavioral changes are not observed in the newborn. Bupivacaine also is approved for spinal anesthesia and is approximately four times more potent and more toxic than mepivacaine and lidocaine. It can be used with or without epinephrine.

Bupivacaine hydrochlorideSupplier

Fengxian xinchenhui Biotechnology Co., Ltd Gold
Tel
0516-89199858-
Email
1947462668@qq.com
Shanghai Biolang biotechnology Co.,Ltd Gold
Email
11179779@qq.com
Shandong Mingfeng Pharmaceutical and Technology Co. Ltd Gold
Email
1345456643@qq.com
Anhui Rencheng Technology Co., Ltd Gold
Tel
Email
admin@ahrencheng.com
Jinan Chenghui Shuangda Chemical Co., Ltd. Gold
Tel
0531-58897046-
Email
1057567120@qq.com