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5-Chloro-1-(4-piperidyl)-2-benzimidazolinone

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5-Chloro-1-(4-piperidyl)-2-benzimidazolinone Basic information

Product Name:
5-Chloro-1-(4-piperidyl)-2-benzimidazolinone
Synonyms:
  • 1-(4-PIPERIDINYL)-1,3-DIHYDRO-5-CHLOROBENZIMIDAZOLONE
  • 5-Chloro-1,3-dihydro-1-(4-piperidinyl)-2H-benzimidazol-2-one
  • 5-CHLORO-1-(4-PIPERIDINYL)-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE
  • 5-CHLORO-1-(4-PIPERIDINYL)-2-BENZIMIDAZOLIDINONE
  • 5-CHLORO-1-(4-PIPERIDINYL)-2-BENZIMIDAZOLINONE
  • 5-CHLORO-1-(4-PIPERIDYL)-2-BENZIMIDAZOLINONE
  • 5-CHLORO-1-DIHYDRO-1-(4-PIPERIDINYL)-2H-BENZOMIDEZOLE-2-ONE
  • 5-CHLORO-1-PIPERIDIN-4-YL-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE
CAS:
53786-28-0
MF:
C12H14ClN3O
MW:
251.71
EINECS:
258-771-6
Product Categories:
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Aromatics, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
  • Benzimidazoles
  • BenzimidazolesHeterocyclic Building Blocks
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
Mol File:
53786-28-0.mol
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5-Chloro-1-(4-piperidyl)-2-benzimidazolinone Chemical Properties

Melting point:
228-231 °C (lit.)
Density 
1.323±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 20℃
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Powder to crystal
pka
11.12±0.30(Predicted)
color 
White to Off-White
Water Solubility 
549mg/L at 20℃
LogP
-0.6 at 20℃
CAS DataBase Reference
53786-28-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HS Code 
29339980

MSDS

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5-Chloro-1-(4-piperidyl)-2-benzimidazolinone Usage And Synthesis

Uses

5-Chloro-1-(4-piperidinyl)-2-benzimidazolidinone (Domperidone EP Impurity A) is a metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).

Uses

5-Chloro-1-(4-piperidyl)-2-benzimidazolinone is a metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).

General Description

5-Chloro-1-(4-piperidyl)-2-benzimidazolinone is a 2-benzimidazolone derivative. It exhibits anti-nauseant properties.

Flammability and Explosibility

Not classified

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