2-Chloro-3-methylpyridine Chemical Properties

Melting point:

193 °C

Boiling point:

192-193 °C/751 mmHg (lit.)

Density 

1.17 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.533(lit.)

Flash point:

175 °F

storage temp. 

Inert atmosphere,Room Temperature

pka

0.75±0.10(Predicted)

form 

Liquid

color 

Colorless to light yellow

Specific Gravity

1.170

BRN 

107895

InChI

InChI=1S/C6H6ClN/c1-5-3-2-4-8-6(5)7/h2-4H,1H3

InChIKey

RKVUCIFREKHYTL-UHFFFAOYSA-N

SMILES

C1(Cl)=NC=CC=C1C

CAS DataBase Reference

18368-76-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-20/21/22

Safety Statements 

26-36-36/37/39

RIDADR 

2810

WGK Germany 

3

HazardClass 

6.1

PackingGroup 

III

HS Code 

29333990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-3-methylpyridine Usage And Synthesis

Description

2-Chloro-3-methylpyridine is an intermediate for many medicines and pesticides, such as fluazifop, nicosulfuron, and fluazifop. Moreover, with the gradual promotion of these new high-efficiency and low-toxic heterocyclic pesticides, 2-chloro-3-methylpyridine is increasing. The industrial method for preparing 2-chloro-3-methylpyridine is to obtain it by site-specific chlorination of 3-methylpyridine. First, 3-methylpyridine is epoxidized and then chlorinated. The main chlorinated 3-methylpyridine is a mixture of 2-chloro-3-methylpyridine and 2-chloro-5-methylpyridine, of which 2-chloro-3-methylpyridine accounts for 20% (mass).

Chemical Properties

colorless to light yellow liquid

Uses

2-Chloro-3-methylpyridine is an active ingredient and a major constituent of imidaclopide, a systemic insecticide that acts as insect neurotoxin and belongs to a class of chemical called the neonicotinoids.

2-Chloro-3-methylpyridine(18368-76-8)Related Product Information

• Azamethiphos
• 2,6-Lutidine
• 5-Amino-2-methylpyridine
• 4-Methylpyridine
• 2,5-Dimethylpyridine
• 2-Chloro-3-nitropyridine
• 2-(Chloromethyl)pyridine
• 2-Chloro-3-cyano-4,6-dimethylpyridine
• PYRIDINITRIL
• ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE
• 2-Chloro-3-(trifluoromethyl)pyridine
• 2-CHLORO-4,6-DIMETHYLNICOTINAMIDE
• 2-Chloro-3-cyanopyridine
• 2,6-Dichloro-4-methylnicotinonitrile
• 2-Chloro-5-chloromethylpyridine
• 2-Chloronicotinic acid
• 2-Chloronicotinamide
• Difluorochloromethane