Paeoniflorin Chemical Properties

Melting point:

approximate 124℃ (dec.)

Boiling point:

498.51°C (rough estimate)

Density 

1.3044 (rough estimate)

refractive index 

1.5376 (estimate)

storage temp. 

2-8°C

solubility 

Methanol (Slightly, Sonicated), Pyridine (Slightly)

pka

11.52±0.70(Predicted)

form 

powder

color 

white

InChIKey

YKRGDOXKVOZESV-WRJNSLSBSA-N

CAS DataBase Reference

23180-57-6(CAS DataBase Reference)

Safety Information

Safety Statements 

24/25

WGK Germany 

3

RTECS 

RT1200000

HS Code 

29389090

Toxicity

LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69

Paeoniflorin Usage And Synthesis

Chemical Properties

White powder

Uses

antiinflammatory, antispasmodic, antihypertensive, antidiuretic

Uses

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic，anti-inflammatory，anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe

Uses

Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.

Definition

ChEBI: Paeoniflorin is a terpene glycoside.

General Description

Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.

Biochem/physiol Actions

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.

Safety Profile

Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.

Paeoniflorin(23180-57-6)Related Product Information

• Albiflorin
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• paeoniflorigenone
• benzoylpaeoniflorin
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• 2-TERT-BUTOXYTETRAHYDROFURAN
• 5,5-DIETHOXYPENTAN-1-OL
• Cyclobutanol
• CYCLOBUTANE-1,1-DIYLDIMETHANOL
• 2,6-dimethyl-1,3-dioxan-4-ol
• Methyl
• Kresoxim-methyl
• Methylparaben
• Paeoniflorin