Paeoniflorin
Paeoniflorin Basic information
- Product Name:
- Paeoniflorin
- Synonyms:
-
- 5beta-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1alpha(2h)-yl-beta-d-glucopyranoside
- PAEONIFLORIN
- 5-alpha,5a-alpha,5b-alpha))-a-alph
- 5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl,(1ar-(1a-alpha,2-beta,3
- Paeoniflorin, 98%, from Paeonia sterniana Fletcher in Journ.
- Paeoniflorin 23180-57-6
- eoniflorin
- Paeoniflorin, ≥98%(HPLC)
- CAS:
- 23180-57-6
- MF:
- C23H28O11
- MW:
- 480.47
- EINECS:
- 245-476-2
- Product Categories:
-
- Heterocycles
- Natural Plant Extract
- The group of Paeoniflorin
- API's
- Steroids
- Veterinaries
- reference substance
- Plant extract
- chemical reagent
- pharmaceutical intermediate
- phytochemical
- reference standards from Chinese medicinal herbs (TCM).
- standardized herbal extract
- Inhibitors
- Mol File:
- 23180-57-6.mol
Paeoniflorin Chemical Properties
- Melting point:
- approximate 124℃ (dec.)
- Boiling point:
- 498.51°C (rough estimate)
- Density
- 1.3044 (rough estimate)
- refractive index
- 1.5376 (estimate)
- storage temp.
- 2-8°C
- solubility
- Methanol (Slightly, Sonicated), Pyridine (Slightly)
- pka
- 11.52±0.70(Predicted)
- form
- powder
- color
- white
- InChIKey
- YKRGDOXKVOZESV-WRJNSLSBSA-N
- CAS DataBase Reference
- 23180-57-6(CAS DataBase Reference)
Safety Information
- Safety Statements
- 24/25
- WGK Germany
- 3
- RTECS
- RT1200000
- HS Code
- 29389090
- Toxicity
- LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69
Paeoniflorin Usage And Synthesis
Chemical Properties
White powder
Uses
Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic，anti-inflammatory，anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe
Uses
Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.
Uses
antiinflammatory, antispasmodic, antihypertensive, antidiuretic
Definition
ChEBI: Paeoniflorin is a terpene glycoside.
General Description
Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.
Biochem/physiol Actions
Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.
Safety Profile
Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.
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