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Paeoniflorin

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Paeoniflorin Basic information

Product Name:
Paeoniflorin
Synonyms:
  • 5beta-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1h-3,4-dioxacyclobuta[cd]pentalen-1alpha(2h)-yl-beta-d-glucopyranoside
  • PAEONIFLORIN
  • 5-alpha,5a-alpha,5b-alpha))-a-alph
  • 5-methano-1h-3,4-dioxacyclobuta(cd)pentalen-1a(2h)-yl,(1ar-(1a-alpha,2-beta,3
  • Paeoniflorin, 98%, from Paeonia sterniana Fletcher in Journ.
  • Paeoniflorin 23180-57-6
  • eoniflorin
  • Paeoniflorin, ≥98%(HPLC)
CAS:
23180-57-6
MF:
C23H28O11
MW:
480.47
EINECS:
245-476-2
Product Categories:
  • Heterocycles
  • Natural Plant Extract
  • The group of Paeoniflorin
  • API's
  • Steroids
  • Veterinaries
  • reference substance
  • Plant extract
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
Mol File:
23180-57-6.mol
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Paeoniflorin Chemical Properties

Melting point:
approximate 124℃ (dec.)
Boiling point:
498.51°C (rough estimate)
Density 
1.3044 (rough estimate)
refractive index 
1.5376 (estimate)
storage temp. 
2-8°C
solubility 
Methanol (Slightly, Sonicated), Pyridine (Slightly)
pka
11.52±0.70(Predicted)
form 
powder
color 
white
InChIKey
YKRGDOXKVOZESV-WRJNSLSBSA-N
CAS DataBase Reference
23180-57-6(CAS DataBase Reference)
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
RTECS 
RT1200000
HS Code 
29389090
Toxicity
LD50 ipr-mus: 9530 mg/kg YKKZAJ 89,879,69
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Paeoniflorin Usage And Synthesis

Chemical Properties

White powder

Uses

Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall. Paeoniflorin has broad pharmacological effects, such as analgesic, anti-diuretic,anti-inflammatory,anti-convulsant, vasodilatic, and etc. In a study, paeoniflorin effe

Uses

Paeoniflorin is an active compound of the Paeonia root. Paeoniflorin inhibits Aβ25-35-induced mitochondrial dysfunction, which includes decreased mitochondrial membrane potential, increased Bax/Bcl-2 ratio, cytochrome c release and activity of caspase-3 and caspase-9. Paeoniflorin could attenuate or restore the viability loss, apoptotic increase, and ROS production induced by Aβ25-35 in SH-SY5Y cells.

Uses

antiinflammatory, antispasmodic, antihypertensive, antidiuretic

Definition

ChEBI: Paeoniflorin is a terpene glycoside.

General Description

Paeoniflorin has been demonstrated to exert anti-inflammatory and immunomodulatory effects.

Biochem/physiol Actions

Herbal constituent of peony root. It is used in Chinese traditional medicine for its spasmolytic and pain-relieving properties. Exhibits anticoagulant, neuromuscular blocking, cognition-enhancing, immunoregulating, and antihyperglycemic effects.

Safety Profile

Moderately toxic by intravenous route. Mildly toxic by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fumes.

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