Basic information Safety Supplier Related

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

Basic information Safety Supplier Related

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Basic information

Product Name:
N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
Synonyms:
  • N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
  • E3 ligase Ligand-Linker Conjugates 18
  • Azido-Thalidomide
  • N-(4-Azidobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetamide
  • Cereblon Ligand-Linker Conjugates 4
  • Thalidomide O amido C4 N3,ThalidomideOamidoC4N3,Inhibitor,inhibit,Thalidomide-O-amido-C-4-N3,E3 Ligase Ligand-Linker Conjugates
  • Thalidomide 4'-oxyacetamide-alkylC4-azide
  • Acetamide, N-(4-azidobutyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
CAS:
2098488-36-7
MF:
C19H20N6O6
MW:
428.3987
Mol File:
2098488-36-7.mol
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N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Chemical Properties

solubility 
DMF: 12 mg/ml; DMSO: 12 mg/ml; DMSO:PBS (pH 7.2)(1:8): 0.11 mg/ml
form 
A crystalline solid
color 
White to off-white
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N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide Usage And Synthesis

Description

UUN 88367, also known as Azido-Thalidomide is a clickable Thalidomide derivative, used as a building block for cereblon. Azido-Thalidomide targets PROTACs by hijacking cereblon as the E3 ubiquitin ligase component. This product has no formal name at the moment.

storage

Store at -20°C

N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamideSupplier

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