ALLOCRYPTOPINE Chemical Properties

Melting point:

169-170 °C

Boiling point:

552.7±50.0 °C(Predicted)

Density 

1.216±0.06 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

7.86±0.20(Predicted)

biological source

plant

Water Solubility 

water: slightly soluble

ALLOCRYPTOPINE Usage And Synthesis

Uses

It is a natural product derived from plant source th at finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Definition

ChEBI: Allocryptopine is a dibenzazecine alkaloid, an organic heterotetracyclic compound, a tertiary amino compound, a cyclic ketone, a cyclic acetal and an aromatic ether.

Biological Activity

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells th at carry mutation channel 24 h.

target

cAMP | P450 (e.g. CYP17)

ALLOCRYPTOPINE(24240-04-8)Related Product Information

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• ALLOCRYPTOPINE
• A-ALLOCRYPTOPINE
• ALLOCRYPTOPINE
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