Exifone
Exifone Basic information
- Product Name:
- Exifone
- Synonyms:
-
- 3,4,5,2',3',4'-HEXAHYDROXYBENZOPHENONE
- (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)methanone
- 2,3,3',4,4',5'-HEXAHYDROXYBENZOPHENONE
- 2,3,4,3',4',5'-HEXAHYDROXY BENZOPHENONE
- EXIFONE
- (2,3,4-trihydroxyphenyl)(3,4,5-trihydroxyphenyl)-methanon
- 4-galloylpyrogallol
- adlone
- CAS:
- 52479-85-3
- MF:
- C13H10O7
- MW:
- 278.21
- EINECS:
- 257-945-9
- Product Categories:
-
- Aromatics
- Intermediates & Fine Chemicals
- Neurochemicals
- Pharmaceuticals
- Mol File:
- 52479-85-3.mol
Exifone Chemical Properties
- Melting point:
- 245°C
- Boiling point:
- 674.6±55.0 °C(Predicted)
- Density
- 1.759±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 6.99±0.40(Predicted)
- color
- Yellow
- Merck
- 3915
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 52479-85-3(CAS DataBase Reference)
MSDS
- Language:English Provider:3,4,5,2',3',4'-Hexahydroxybenzophenone
Exifone Usage And Synthesis
Description
Exifone is a nootropic indicated for the treatment of cognitive dysfunctions in geriatric patients. Its reported clinical efficacy is ascribed to pharmacological activities including activation of neuronal oxygen and glucose metabolism, free radical scavenging, and indirect effects on serotonergic and dopaminergic pathways.
Chemical Properties
yellow amorphous powder
Originator
Pharmascience (France)
Uses
Exifone is a nootropic drug and cognitive enhancing agent. Exifone is a free radical scavenger shown to have protective effects againts Exifone has been shown to antagonize amnesias induced by benzodiazepines in mice.
Preparation
Preparation by condensation of gallic acid with pyrogallol,
? in the presence of zinc chloride at 120° (good yield) or at 145° for 3 h (Nencki reaction);
? in the presence of zinc chloride and phosphorous oxychloride at 80° for 2 h, via Fries rearrangement.
Definition
ChEBI: (2,3,4-trihydroxyphenyl)-(3,4,5-trihydroxyphenyl)methanone is a member of benzophenones.
brand name
Adlone
Exifone Preparation Products And Raw materials
Raw materials
ExifoneSupplier
- Tel
- 010-82848833 400-666-7788
- jkinfo@jkchemical.com
- Tel
- 021-67121386
- Sales-CN@TCIchemicals.com
- Tel
- 021-021-58432009 400-005-6266
- sales8178@energy-chemical.com
- Tel
- 1-(800)-881-8210
- inquiries@lgmpharma.com
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- sales@maya-r.com