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Pregnenolone acetate

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Pregnenolone acetate Basic information

Product Name:
Pregnenolone acetate
Synonyms:
  • 17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ACETATE
  • 3 BETA,21-DIHYDROXY-5-PREGNEN-20-ONE-3-ACETATE
  • 3-BETA-HYDROXY-5-PREGNEN-20-ONE 3-ACETATE
  • 3BETA-ACETOXY-5-PREGNEN-20-ONE
  • ACETIC ACID (3S,8S,9S,10R,13S,14S,17S)-17-ACETYL-10,13-DIMETHYL-2,3,4,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-3-YL ESTER
  • ACETOXYPREGNENOLONE
  • 5-PREGNEN-3BETA-OL-20-ONE 3-ACETATE
  • 5-PREGNEN-3BETA-OL-20-ONE ACETATE
CAS:
1778-02-5
MF:
C23H34O3
MW:
358.51
EINECS:
217-212-6
Product Categories:
  • Agonist
  • Biochemistry
  • Steroids
  • Steroids (Others)
Mol File:
1778-02-5.mol
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Pregnenolone acetate Chemical Properties

Melting point:
149-152 °C(lit.)
alpha 
22 º (c=2, C2H5OH 23 ºC)
Boiling point:
430.93°C (rough estimate)
Density 
1.0816 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form 
Solid
color 
White
optical activity
[α]20/D +19°, c = 1 in ethanol
Merck 
14,7733
BRN 
2062850
InChIKey
CRRKVZVYZQXICQ-RJJCNJEVSA-N
CAS DataBase Reference
1778-02-5(CAS DataBase Reference)
NIST Chemistry Reference
3Beta-acetoxypregn-5-en-20-one(1778-02-5)
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Safety Information

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29153900

MSDS

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Pregnenolone acetate Usage And Synthesis

Chemical Properties

white to light yellow crystalline powder or Crystallized (methanol).

Uses

Pregnenolone acetate is an intermediate in the synthesis of progesterone. It is uses as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. It has also been shown to stimulate locomotor activity and neuronal function in rats.

Preparation

Pregnenolone acetate can be prepared by catalytic hydrogenation (16-position double bond) of 16-Dehydropregnenolone acetate.

Definition

Pregnenolone acetate is a steroid ester. It is a pregnenolone derivative, a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.

Pregnenolone acetate Preparation Products And Raw materials

Raw materials

Pregnenolone acetateSupplier

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