BIOTIN-XX-NHS
BIOTIN-XX-NHS Basic information
- Product Name:
- BIOTIN-XX-NHS
- Synonyms:
-
- N-SUCCINIMIDYL N-6-(BIOTINYLAMINO)CAP- &
- 6-(BIOTINAMIDOCAPROYLAMIDO)CAPROIC ACID N-HYDROXYSU
- n-Succinimidyln-6-(biotinylamino)caproyl-6-aminocaproatabout90%
- interMediate of 6-((+)-BiotinaMidohexanoylaMino)hexanoic acid N-hydroxysucciniMide ester
- 6-[6-(Biotinylamino)hexanoylamino]hexanoicacidN-hydroxysuccinimideester
- 5-[5-(N-SUCCINIMIDYLOXYCARBONYL)PENTYLAMIDO]HEXYL D-BIOTINAMIDE (BIOTIN-(AC5)2-OSU)
- 6-((+)-Biotinamidohexanoylamino)hexanoic acid N-hydroxysuccinimide ester
- Biotin-X-X-NHS, N-Succinimidyl N-[6-(biotinylamino)caproyl]-6-aminocaproate, 6-(Biotinamidocaproylamido)caproic acid N-hydroxysuccinimide ester
- CAS:
- 89889-52-1
- MF:
- C26H41N5O7S
- MW:
- 567.7
- EINECS:
- 205-525-8
- Product Categories:
-
- Biotin Derivatives
- Cross Linking Reagents
- Mol File:
- 89889-52-1.mol
BIOTIN-XX-NHS Chemical Properties
- Melting point:
- 147-151°C
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMF: 25 mg/mL
- pka
- 13.90±0.40(Predicted)
- form
- powder
- color
- White to Almost white
- Appearance
- light beige solid
- BRN
- 8377428
- Stability:
- Moisture Sensitive
- InChIKey
- ATYCFNRXENKXSE-MHPIHPPYSA-N
- SMILES
- C1(=O)N[C@]2([H])[C@H](CCCCC(NCCCCCC(NCCCCCC(ON3C(=O)CCC3=O)=O)=O)=O)SC[C@]2([H])N1
- CAS DataBase Reference
- 89889-52-1
Safety Information
- WGK Germany
- 3
- F
- 10-21
- HS Code
- 29349990
MSDS
- Language:English Provider:SigmaAldrich
BIOTIN-XX-NHS Usage And Synthesis
Description
Biotin-LC-LC-NHS is a biotinylation reagent that contains an N-hydroxysuccinimide (NHS) moiety, which activates carboxylic acid groups on biotin to facilitate coupling reactions, and a 30.5 Å spacer to decrease steric hindrance. It has been used to biotinylate small molecules such as paclitaxel and coenzyme Q10 for use in binding site characterization.
Chemical Properties
White Solid
Uses
trifunctional aziridine reagent very reactive for active hydrogen groups
Uses
Biotinamidohexanoyl-6-aminohexanoic acid N-hydroxysuccinimide ester has been used in human IgM biotinylation.
Uses
A biotinylated cross-linking reagent.
References
[1] LEV. G. LIS, Vadim J. Gurvich*. Synthesis and Biological Evaluation of a Biotinylated Paclitaxel with an Extra-Long Chain Spacer Arm[J]. ACS Medicinal Chemistry Letters, 2012, 3 9: 745-748. DOI: 10.1021/ml300149z
[2] MASATOSHI MURAI. Characterization of the Ubiquinone Binding Site in the Alternative NADH-Quinone Oxidoreductase of Saccharomyces cerevisiae by Photoaffinity Labeling[J]. Biochemistry Biochemistry, 2010, 49 13: 2973-2980. DOI: 10.1021/bi100005j
BIOTIN-XX-NHSSupplier
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BIOTIN-XX-NHS(89889-52-1)Related Product Information
- ATBTA-EU3+
- D-Biotin
- BIOTIN HYDRAZIDE
- (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID
- Succinimidyl 6-(biotinamido)hexanoate
- BIOTIN-NHS
- Biotin-LC-PEG4-NHS ester
- alpha-MaleiMidopropionyl-oMega-succiniMidyl-10(ethylene glycol)
- O-(2-CARBOXYETHYL)POLYETHYLENE GLYCOL
- 5,8,11,14-Tetraoxa-2-azahexadecanedioic acid
- Amino-PEG4-acid
- BIOTINAMIDOCAPROYL HYDRAZIDE
- D-BIOTIN P-NITROPHENYL ESTER
- Biotin-SLC
- BIOTIN-2X
- Biotin-NHCH2CH2-SS-Pyr
- Biotin-LC-PEG9-NHS ester
- Biotin-LC-PEG1-NHS ester