Terephthalaldehyde Chemical Properties

Melting point:

114-116 °C (lit.)

Boiling point:

245-248 °C (lit.)

Density 

1,06 g/cm³

vapor pressure 

0.25-0.46Pa at 20-25℃

refractive index 

1.4800 (estimate)

Flash point:

76 °C

storage temp. 

Store below +30°C.

solubility 

3g/l

form 

Crystalline Powder

color 

White to light yellow

Water Solubility 

3 g/L (50 ºC)

Sensitive 

Air Sensitive

BRN 

385863

InChIKey

KUCOHFSKRZZVRO-UHFFFAOYSA-N

LogP

1 at 20.1℃ and pH6.6-6.8

CAS DataBase Reference

623-27-8(CAS DataBase Reference)

NIST Chemistry Reference

1,4-Benzenedicarboxaldehyde(623-27-8)

EPA Substance Registry System

1,4-Benzenedicarboxaldehyde (623-27-8)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-36/37

Safety Statements 

22-24/25-36-26-37/39

WGK Germany 

1

RTECS 

WZ0430000

Hazard Note 

Irritant

TSCA 

Yes

HS Code 

29122900

Hazardous Substances Data

623-27-8(Hazardous Substances Data)

MSDS

• Language:English Provider:1,4-Phthalaldehyde
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Terephthalaldehyde Usage And Synthesis

Description

Terephthalaldehyde is an aromatic dialdehyde. Theoretically, the two aldehydes of terephthalaldehyde (TPA) are equivalent, so the single or double Schiff base from TPA and d-glucosamine (Glc) may be formed at the same time. It is used as an intermediate for the preparation of dyes and fluorescent whitening agents and in the synthesis of polyimines by reacting with aliphatic diamines. It is also used as a precursor for the preparation of paramagnetic microporous polymeric organic frameworks (POFs) through copolymerization with pyrrole, indole, and carbazole. As a good crosslinking agent, it could used in crosslinked chitosan hydrogel for the selective removal of anionic dyes[1].

Chemical Properties

WHITE TO LIGHT YELLOW CRYSTALLINE POWDER

Uses

Terephthalaldehyde (cas# 623-27-8) is a compound useful in organic synthesis.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 3, p. 788, 1955
Tetrahedron Letters, 36, p. 2285, 1995 DOI: 10.1016/0040-4039(95)00191-E

Purification Methods

Terephthalaldehyde [623-27-8] M 134.1, m 116o, b 245 -248o/771mm. Crystallise terephthalaldehyde from water. [Beilstein 7 IV 2140.]

References

[1] Weng Q, et al. Controllable Synthesis and Biological Application of Schiff Bases from d-Glucosamine and Terephthalaldehyde. ACS Omega, 2020; 5: 24864–24870.

Terephthalaldehyde(623-27-8)Related Product Information

• Terephthalic acid
• 4-Hydroxybenzaldehyde
• p-Anisaldehyde
• mono-Methyl terephthalate
• Terephthaloyl chloride
• 1,4-Dimethoxybenzene
• 1,4-Dicyanobenzene
• Dioctyl terephthalate
• Pyromellitic acid
• 1,2,4-Benzenetricarboxylic acid
• ANTHRAQUINONE-2-CARBOXYLIC ACID
• Pyromellitic Dianhydride
• 2-Bromoterephthalic acid
• MELLITIC ACID
• 4-Acetylbenzoic acid
• 3,3',4,4'-Benzophenonetetracarboxylic dianhydride
• Trimellitic Anhydride
• o-Phthalaldehyde