3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE Chemical Properties

Melting point:

191-193 °C (lit.)

Boiling point:

440.52°C (rough estimate)

Density 

1.2028 (rough estimate)

refractive index 

1.6400 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

form 

powder to crystal

pka

-0.06±0.63(Predicted)

color 

Light yellow to Yellow to Orange

Water Solubility 

Soluble in water.

BRN 

542151

Stability:

Stable. Incompatible with strong acids, strong oxidizing agents.

CAS DataBase Reference

1046-56-6(CAS DataBase Reference)

EPA Substance Registry System

1,2,4-Triazine, 5,6-diphenyl-3-(2-pyridinyl)- (1046-56-6)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

XY8598150

TSCA 

Yes

HS Code 

29336990

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE Usage And Synthesis

Chemical Properties

yellow powder

Uses

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine was employed as chromogenic-extraction reagent during spectrophotometric determination of iron in acids and acidic solutions. It was also employed as precolumn derivatizing reagent in the HPLC method with UV absorbance detection for the Fe(II) determination.

Indications

PDT with 20% ALA may be used for the treatment of actinic keratoses. The product is marketed as Levulan Kerastick (DUSA Pharmaceuticals, Valhalla, New York). The ALA is applied diffusely over the field with an applicator; the patient returns 1 to 3 hours later and is exposed to an activating light source. Once exposed to the light, ALA produces singlet oxygen, which damages the cell membrane. Sixty-six percent of patients had total clearing of lesions at 8 weeks using blue light exposure for 15 minutes. Patients experience a burning pain but heal with an excellent cosmetic result. Photosensitivity lasts for 24 hours. An optional regimen is to apply ALA only to visible actinic keratoses; however, this method will not treat subclinical lesions. A variety of lasers and light sources can be used to activate the ALA, including blue light, yellow light, and broadband light; however, many details remain to be worked out, such as the optimal incubation times for the ALA when using each of the various light sources.

Definition

ChEBI: 5,6-diphenyl-3-(2-pyridyl)-1,2,4-triazine is a member of 1,2,4-triazines.

General Description

3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine (PDT) reacts with Cu(II) perchlorate in ethanol to yield [Cu(PDT)₂(ClO₄)₂].

Purification Methods

Purify it by repeated recrystallisation from EtOH/dimethylformamide. It is a reagent for estimating Fe(II) and Ru(II). [Chriswell & Schilt Anal Chem 46 992 1974, Kamra & Ayers Anal Chem 78 423 1975.]

3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE(1046-56-6)Related Product Information

• 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE
• Ferrozine disodium salt
• Ferrozine sodium
• 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE-P,P'-DISULFONIC ACID, DISODIUM SALT HYDRATE, 98+%
• 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,pμ-disulfonic acid hydrate monosodium salt
• 2,4-BIS[5,6-DI(P-SULFOPHENYL)-1,2,4-TRIAZIN-3-YL]PYRIDINE TETRASODIUM SALT
• 1,2,4-Triazine
• 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine-p,p'-disulfonic acid, disodium salt hydrat
• 2,4-BDTP
• FERROZINE IRON REAGENT, HYDRATE, PURE, 98+%
• FERROZINE(R) IRON REAGENT
• 5,6-DIPHENYL-1,2,4-TRIAZINE
• 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE-P,P'-DISULFONIC ACID MONOSODIUM SALT
• 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine sulfonate, sodium salt
• 3-[2-(5,6-diphenyl-1,2,4-triazin-3-yl)-4-pyridyl]-5,6-diphenyl-1,2,4-triazine
• 3-(2-PYRIDYL)-5,6-BIS(4-SULFOPHENYL)-1,2,4-TRIAZINE DISODIUM SALT HYDRATE
• 3-(2-PYRIDYL)-5,6-DIPHENYL-1,2,4-TRIAZINE DEPOSITED ON AMBERLITED-2
• 3-(2-Pyridyl)-5,6-diphenyl-1,2,4-triazine disulfonic acid, disodium salt