N-DESMETHYL ZOLMITRIPTAN HCL Chemical Properties

Melting point:

63-66°C

Boiling point:

577.7±35.0 °C(Predicted)

Density 

1.235±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer

solubility 

DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)

form 

Solid

pka

12.57±0.40(Predicted)

color 

Light Yellow to Light Brown

Stability:

Hygroscopic

CAS DataBase Reference

139264-35-0

Safety Information

HS Code 

2934990002

N-DESMETHYL ZOLMITRIPTAN HCL Usage And Synthesis

Description

N-desmethyl Zolmitriptan (DZT) is an active metabolite of the serotonin (5-HT) receptor subtype 5-HT_1B and 5-HT_1D agonist zolmitriptan . DZT is an agonist of 5-HT_1B receptors that induces contraction of isolated human cerebral arteries (EC₅₀ = 100 nM).

Chemical Properties

Pale Yellow Solid

Uses

A metabolite of Zolmitriptan (Z639000). Zolmitriptan USP Related Compound A.

N-DESMETHYL ZOLMITRIPTAN HCL(139264-35-0)Related Product Information

• Zolmitriptan N-Oxide
• Zolmitriptan
• (S)-4-(4'-Nitrobenzyl)-1,3-oxazolidine-2-one
• 2-Oxazolidinone, 4-[(2,3,4,9-tetrahydro-2-methyl-1H-pyrido[3,4-b]indol-6-yl)methyl]-, (4S)-
• (S)-4-(4-Aminobenzyl)-2(1H)-oxazolidinone
• (S)-3-(2-(dimethylamino)ethyl)-5-((2-oxooxazolidin-4-yl)methyl)-1H-indole-2-carboxylic acid
• N-Desmethyl Zolmitriptan-d3
• (S)-4-(4-Nitrobenzyl)-2-oxazolidinone
• Sumatriptan
• Zolmitriptan
• Zolmitriptan Related Compound D (20 mg) ((S)-Ethyl 3-[2-(dimethylamino)ethyl]-5-[(2-oxooxazolidin-4-yl)methyl]-1H-indole-2-carboxylate)
• Didesmethyl Zolmitriptan
• Zolmitriptan Related Compound B (20 mg) ((S)-2-Amino-3-{3-[2-(dimethylamino)ethyl]-1H-indol-5-yl}propan-1-ol)
• Zolmitriptan Related Compound F
• N-DESMETHYL ZOLMITRIPTAN HCL