AYANIN
AYANIN Basic information
- Product Name:
- AYANIN
- Synonyms:
-
- QUERCETIN 3,7,4'-TRIMETHYL ETHER
- AYANIN
- 2-(3-Hydroxy-4-methoxyphenyl)-3,7-dimethoxy-5-hydroxy-4H-1-benzopyran-4-one
- 3',5-Dihydroxy-3,4',7-trimethoxyflavone
- 3,7,4'-Tri-O-methylquercetin
- 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,7-dimethoxy-4H-1-benzopyran-4-one
- Quercetin 3,4',7-trimethyl ether
- 4H-1-Benzopyran-4-one,5-hydroxy-2-(3-hydroxy-4-Methoxyphenyl)-3,7-diMethoxy-
- CAS:
- 572-32-7
- MF:
- C18H16O7
- MW:
- 344.32
- Mol File:
- 572-32-7.mol
AYANIN Chemical Properties
- Melting point:
- 173℃
- Boiling point:
- 600.8±55.0 °C(Predicted)
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- 4°C, protect from light
- form
- Solid
- pka
- 6.15±0.40(Predicted)
- color
- White to yellow
AYANIN Usage And Synthesis
Uses
Ayanin is a bioflavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase inhibitor.
Definition
ChEBI: 3',5-dihydroxy-3,4',7-trimethoxyflavone is a trimethoxyflavone that is quercetin in which the hydroxy groups at positions 3, 4' and 7 have been replaced by methoxy groups. It has a role as a plant metabolite. It is a dihydroxyflavone and a trimethoxyflavone. It is functionally related to a quercetin. It is a conjugate acid of a 3',5-dihydroxy-3,4',7-trimethoxyflavone(1-).
Biological Activity
Ayanin is a biologically active flavonoid isolated from Croton schiedeanus Schlecht. Ayanin is a non-selective phosphodiesterase (phosphodiesterase1-4) inhibitor, which can be used in the study of respiratory diseases, such as allergic asthma.
in vitro
Ayanin inhibits interleukin (IL)-4 production from purified basophils with an IC 50 value of 2.2 μM.
target
| PDE2A
| PDE4
|