METHYL 1-BROMOCYCLOHEXANECARBOXYLATE Chemical Properties

Boiling point:

115-116 °C/19 mmHg (lit.)

Density 

1.39 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.493(lit.)

Flash point:

222 °F

storage temp. 

2-8°C

Safety Information

Hazard Codes 

C

Risk Statements 

34-36/37

Safety Statements 

26-27-28-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

HazardClass 

8

PackingGroup 

III

MSDS

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METHYL 1-BROMOCYCLOHEXANECARBOXYLATE Usage And Synthesis

Uses

Methyl 1-bromocyclohexanecarboxylate may be used in the improved method of preparation of methyl 3-oxo-1-cyclohexene-1-carboxylate. It may be used in the Reformatsky synthesis of 16-aryl-15-oxadispiro[5.1.5.3]hexadecane-7,14-diones.

General Description

Methyl 1-bromocyclohexanecarboxylate reacts with zinc and substituted chalcones to yield the corresponding spiro-3,4-dihydropyran-2-one derivatives, 3-aryl-5-aryl-2-oxaspiro[5.5]undec-3-en-1-ones. Reformatsky reaction of methyl 1-bromocyclohexanecarboxylate with 2-aryl-2-oxoacetaldehyde is reported. Methyl 1-bromocyclohexanecarboxylate reacts with zinc and amides or methylamides of 3-aryl-2-cyanopropenoic acids to yield 5-aryl-1,3-dioxo-2-azaspiro[5.5]undecane-4-carbonitriles or 5-aryl-2-methyl-1,3-dioxo-2-azaspiro[5.5]undecane-4-carbonitriles.

METHYL 1-BROMOCYCLOHEXANECARBOXYLATE(3196-23-4)Related Product Information

• Methyl 2-bromo-2-methylpropionate
• S-2--Bromobutyric acid
• METHYL 2-BROMOVALERATE
• (S)-(-)-2-BROMOPROPIONIC ACID
• METHYL 2-BROMOHEXANOATE
• 2-Bromovaleric acid
• (R)-(+)-2-BROMOPROPIONIC ACID
• 2-Bromo-2-Methylbutyric Acid
• 2-Bromo-2-methylpropionic acid
• DL-2-Bromohexanoic acid
• (R)-2-BROMOBUTANOIC ACID
• Bromocyclohexane
• 2-BROMODIETHYLACETIC ACID
• A-BROMOHEPTANOIC ACID
• 3-BROMO-3-METHYLPENTANE
• METHYL 1-BROMOCYCLOHEXANECARBOXYLATE
• 2-BROMO-2-METHYLPENTANE
• DIMETHYL 1,4-DIBROMOCYCLOHEXANE-1,4-DICARBOXYLATE