DL-Norvaline Chemical Properties

Melting point:

≥300 °C (dec.)

Boiling point:

222.9±23.0 °C(Predicted)

Density 

1.2000 (estimate)

refractive index 

1.4650 (estimate)

storage temp. 

Store below +30°C.

solubility 

83.9g/l

pka

2.36, 9.72(at 25℃)

form 

Solid

color 

White to Off-White

optical activity

[α]25/D 0.00±0.10°, c = 2 in 5 M HCl

Water Solubility 

1 g/10 mL (18 ºC)

Merck 

14,6716

BRN 

1721163

InChIKey

SNDPXSYFESPGGJ-UHFFFAOYSA-N

CAS DataBase Reference

760-78-1(CAS DataBase Reference)

NIST Chemistry Reference

(Dl) 2-aminopentanoic acid(760-78-1)

EPA Substance Registry System

Norvaline (760-78-1)

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22-36/37/38-20/22

Safety Statements 

22-24/25-37/39-26-44-35-28-7-4

WGK Germany 

3

TSCA 

Yes

HS Code 

29224995

MSDS

• Language:English Provider:DL-Norvaline
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

DL-Norvaline Usage And Synthesis

Chemical Properties

white to off-white crystals or crystalline powder

Uses

DL-Norvaline is a neurotransmitter.

Uses

DL-Norvaline has been used as an internal standard:

• to analyze metabolites in cultured mammalian cells by gas chromatography-mass spectrometry (GC-MS)
• to convert cysteine and cystine to Cys MPA (S-2-carboxyethylthio-L-cysteine) and quantify the same using a high-performance liquid chromatography (HPLC) analyzer
• for free amino acid analysis in samples of oocytes by liquid chromatography

Definition

ChEBI: An alpha-amino acid that is valeric acid which is substituted at position 2 by an amino group.

General Description

DL-Norvaline, a non-protein amino acid, is of significance in metabolic pathways. It is used as a food additive on account of its nutritional and functional characteristics that are beneficial to health.

Biochem/physiol Actions

Norvaline mediates physiological and pathophysiological processes promoting nitric oxide production. It is used to treat Alzheimer′s disease and is effective against artificial metabolic syndrome in rats. Norvaline exhibits phase transition upon cooling below 190 K and hence it is useful in molecular machines. DL-Norvaline serves as a prototype for research in polymorphism and molecular dynamics of aliphatic α-amino acids containing linear side-chain. It influences the activity, stability, and side-chain packaging of proteins.

DL-Norvaline(760-78-1)Related Product Information

• Estradiol valerate
• MAGNESIUM DIPROPYLACETATE HYDRATE
• 2-Propylpentanoic acid
• Folic acid
• 5-Aminolevulinic acid hydrochloride
• Ethyl 2-(Chlorosulfonyl)acetate
• Pivalic acid
• Valeric acid
• L-Norvaline
• DL-Malic acid
• D(-)-Norvaline
• 5-AMINOVALERIC ACID
• DL-Valine
• Valine
• Ascoric Acid
• L(+)-Arginine
• H-GAMMA-GLU-GLU-OH
• L-Leucine