Palmitoyl-L-Carnitine Chloride
Palmitoyl-L-Carnitine Chloride Basic information
- Product Name:
- Palmitoyl-L-Carnitine Chloride
- Synonyms:
-
- O-PALMITOYL-L-CARNITINE CHLORIDE
- PALMITOYL-L-CARNITINE CHLORIDE
- Palmitoyl-L-carnitine hydrochloride
- (R)-[3-carboxy-2-[(1-oxohexadecyl)oxy]propyl]trimethylammonium chloride
- HEXADECANOYL-L-CARNITINE CHLORIDE
- 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-(1-oxohexadecyl)oxy-, chloride, (2R)-
- L-Palmitoylcarnitine chloride
- 1-Propanaminium, 3-carboxy-N,N,N-trimethyl-2-((1-oxohexadecyl)oxy)-, chloride, (R)-
- CAS:
- 18877-64-0
- MF:
- C23H46ClNO4
- MW:
- 436.07
- EINECS:
- 242-642-6
- Mol File:
- 18877-64-0.mol
Palmitoyl-L-Carnitine Chloride Chemical Properties
- Melting point:
- 168-172 °C(lit.)
- storage temp.
- -20°C
- solubility
- H2O: 25 mg/mL with heat or sonication
- form
- powder
- color
- white
- BRN
- 4071005
- CAS DataBase Reference
- 18877-64-0
MSDS
- Language:English Provider:SigmaAldrich
Palmitoyl-L-Carnitine Chloride Usage And Synthesis
Chemical Properties
White crystalline powder
Uses
Palmitoyl-L-carnitine Hydrochloride is a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Lauroyl-L-carnitine can be diagnostic for a number of ?-oxidation defects.
Uses
Palmitoyl-L-carnitine chloride has been used as acylcarnitine in treating cardiomyocytes for the induction of reactive oxygen species (ROS).
Biochem/physiol Actions
Long-chain acylcarnitine and well-known intermediate in mitochondrial fatty acid oxidation. Modifies myocardial levels of high-energy phosphates and free fatty acids in the heart. Increases erythroid colony formation in culture. Reduces surface negative charge of erythrocytes and myocytes. Reported to affect currents and inhibit endothelium-dependent relaxation induced by acetylcholine and substance P in a dose-dependent manner by suppressing the intracellular calcium signal transduction in endothelial cells. Inhibits the Na/K pump current but has no effect on the intracellular calcium current in guinea pig ventricular cells. However, like oubain, it reversibly depolarizes the resting membrane, decreases action potential duration, and increases the amplitude of myocyte contractions.
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Palmitoyl-L-Carnitine Chloride(18877-64-0)Related Product Information
- PALMITOYL CARNITINE
- Palmitoyl-L-Carnitine Chloride
- DL-Carnitine hydrochloride
- O-Acetyl-L-carnitine hydrochloride
- (3-CARBOXYPROPYL)TRIMETHYLAMMONIUM CHLORIDE
- PROPIONYLCHOLINE CHLORIDE
- BUTYRYLCHOLINE CHLORIDE
- Acetylcholine chloride
- Propionyl-L-carnitine hydrochloride
- 4-DIMETHYLAMINOBUTYRIC ACID HYDROCHLORIDE
- STEAROYL-L-CARNITINE CHLORIDE
- METHACHOLINE CHLORIDE
- (R)-(-)-AMINO-3-HYDROXYBUTANOIC ACID
- (+/-)-OCTANOYLCARNITINE CHLORIDE
- PALMITOYL-D-CARNITINE CHLORIDE
- L(-)-Carnitine hydrochloride
- L-carnitine
- DL-DECANOYLCARNITINE CHLORIDE