Basic information Safety Supplier Related

Everolimus Hydrolized Impurity

Basic information Safety Supplier Related

Everolimus Hydrolized Impurity Basic information

Product Name:
Everolimus Hydrolized Impurity
Synonyms:
  • Everolimus Open-Ring Acid Impurity
  • seco Everolimus B (~90%)
  • Everolimus Impurity 37
  • 2-Piperidinecarboxylic acid, 1-[2-[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R,13R,14R,15E,17R,20S,21R)-14,20-dihydroxy-22-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-2,13-dimethoxy-3,9,11,15,17,21-hexamethyl-12,18-dioxo-3,5,7,15-docosatetraen-1-yl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]-2-oxoac...
CAS:
769905-89-7
MF:
C53H85NO15
MW:
976.26
Mol File:
769905-89-7.mol
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Everolimus Hydrolized Impurity Chemical Properties

Melting point:
>110°C (dec.)
Boiling point:
1010.0±75.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
3.24±0.20(Predicted)
color 
Light Beige to Brown
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Everolimus Hydrolized Impurity Usage And Synthesis

Uses

seco Everolimus B is a metabolite of Everolimus (E945400); an immunosuppressant macrolide and analog of the parent drug Rapamycin (R124000). Everolimus inhibits cytokine-mediated lymphocyte proliferation.

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