Basic information Safety Supplier Related

KetoconazoleN-Oxide

Basic information Safety Supplier Related

KetoconazoleN-Oxide Basic information

Product Name:
KetoconazoleN-Oxide
Synonyms:
  • KetoconazoleN-Oxide
  • Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-oxido-1-piperazinyl]-, rel-
  • Ketoconazole N-Oxide (and enantiomer)
  • 1-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide
  • rel-1-(4-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-4-acetylpiperazine 1-oxide (Ketoconazole Impurity)
CAS:
254912-65-7
MF:
C26H28Cl2N4O5
MW:
547.43
Mol File:
254912-65-7.mol
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KetoconazoleN-Oxide Chemical Properties

pka
6.88±0.12(Predicted)
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KetoconazoleN-Oxide Usage And Synthesis

Uses

Ketoconazole N-?Oxide is an impure analogue of Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. Antimetastatic and antineoplastic activity. Orally active 5-lipoxygenase and thromboxane synthase inhibitor.

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