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Abacavir Impurity F

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Abacavir Impurity F Basic information

Product Name:
Abacavir Impurity F
Synonyms:
  • 6-N-cyclopropyl-9-[(1R,4S)-4-[(2-methylpropan-2-yl)oxymethyl]cyclopent-2-en-1-yl]purine-2,6-diamine
  • Abacavir Impurity 6(Abacavir EP Impurity F)
  • (Abacavir EP Impurity F)
  • Abacavir impurity 3
  • Abacavir EP Imp F
  • Abacavir t-Butyl Ether
  • 6-(Cyclopropylamino)-9-[(1R,4S)-4-[[(1,1-dimethylethyl)oxy]methyl]cyclopent-2-enyl]-9H-purine-2-amine
  • 9H-Purine-2,6-diamine, N6-cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-
CAS:
1443421-68-8
MF:
C18H26N6O
MW:
342.44
Mol File:
1443421-68-8.mol
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Abacavir Impurity F Chemical Properties

Boiling point:
580.3±60.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
4.86±0.10(Predicted)
color 
Pale Orange to Light Orange
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Abacavir Impurity F Usage And Synthesis

Uses

N6-Cyclopropyl-9-[(1R,4S)-4-[(1,1-dimethylethoxy)methyl]-2-cyclopenten-1-yl]-9H-purine-2,6-diamine (Abacavir EP Impurity F) is an impurity of Abacavir (A104990), a guanosine analog that inhibits reverse transcriptase (NRTI)?(1,2).

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