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Loratadine Impurity 17

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Loratadine Impurity 17 Basic information

Product Name:
Loratadine Impurity 17
Synonyms:
  • 8-chloro-6,11-dihydro-5H-benzo[5,6] cyclohepta[1,2-b]pyridin-11-ol
  • 8-Chloro-5,6-dihydro-11H-benzo-[5,6]-cyclohepta-[1,2-b]-pyridin-11-ol
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol, 8-chloro-6,11-dihydro-
  • Loratadine EP Impurity 11
  • Oxiracetam Impurity 29
CAS:
133330-72-0
MF:
C14H12ClNO
MW:
245.7
Mol File:
133330-72-0.mol
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Loratadine Impurity 17 Chemical Properties

Boiling point:
412.2±45.0 °C(Predicted)
Density 
1.321±0.06 g/cm3(Predicted)
pka
12.50±0.20(Predicted)
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Loratadine Impurity 17 Usage And Synthesis

Uses

8-Chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol is an intermediate in the synthesis of 12-Fluoro Dihydroloratadine (F532130), an impurity of Loratadine (L469575), a nonsedating-type histamine H1-receptor.

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