3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE Chemical Properties

Melting point:

58-61 °C(lit.)

Boiling point:

73 °C1 mm Hg(lit.)

Density 

0.9938 (rough estimate)

refractive index 

1.4610 (estimate)

storage temp. 

-20°C

solubility 

DMSO: Soluble: = 10 mg/ml
Ethanol: Soluble: = 10 mg/mlPBS (pH 7.2): Soluble: = 10 mg/ml

pka

2.50±0.60(Predicted)

form 

powder to crystal

color 

White to Orange to Green

CAS DataBase Reference

10135-38-3

Safety Information

Safety Statements 

24/25

WGK Germany 

3

HS Code 

29339980

MSDS

• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich

3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE Usage And Synthesis

Chemical Properties

white to light yellow adhering crystalline chunks

Uses

TMPO is a pyrroline-based N-oxyl spin trap. TMPO is described for use as a cell-permeable spin trap probe for ESR studies of biological systems.

General Description

The ESR spectrum of 3,3,5,5-tetramethyl-1-pyrroline N-oxide was studied.

References

[1] GARRY R. BUETTNER  Bradley E B. The spin trapping of superoxide with M4PO (3,3,5,5-Tetramethylpyrroline-N-oxide)[J]. Free Radical Biology and Medicine, 1990, 8 1: Pages 57-60. DOI: 10.1016/0891-5849(90)90145-9
[2] MICHAEL J. DAVIES  Sarah L S  Luigi G Forni. Electron spin resonance and pulse radiolysis studies on the spin trapping of sulphur-centered radicals[J]. Chemico-Biological Interactions, 1987, 61 2: Pages 177-188. DOI: 10.1016/0009-2797(87)90038-x
[3] A F SLATER. Nitrone spin traps and a nitroxide antioxidant inhibit a common pathway of thymocyte apoptosis.[J]. Biochemical Journal, 1995, 306 ( Pt 3): 771-778. DOI: 10.1042/bj3060771

3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE(10135-38-3)Related Product Information

• 2-Styryl-3,3,5,5-tetramethyl-1-pyrroline 1-oxide
• 2,4,5,5-Tetramethyl-1-pyrroline 1-oxide
• 2,2,5,5-Tetramethyl-3-pyrroline 1-oxide
• 5,5-DIMETHYL-1-PYRROLINE N-OXIDE
• tert-Octylamine
• isobutyraldehyde oxime
• Acetaldoxime
• TERT-BUTYLAZOMETHINE
• Butyraldehyde oxime
• 2-METHYLVALERALDEHYDE OXIME
• 3,3,5,5-TETRAMETHYL-1-PYRROLINE N-OXIDE
• 3,3-DIMETHYLBUTYLAMINE