ChemicalBook > Product Catalog > Organic Chemistry > Alcohols,Phenols,Phenol alcohols > Dodecaethylene glycol
Dodecaethylene glycol
Dodecaethylene glycol Basic information
- Product Name:
- Dodecaethylene glycol
- Synonyms:
-
- PED-DIOL (N=12)
- DODECAETHYLENE GLYCOL
- HO-PEG(12)-OH
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diol (9CI )
- HO-dPEG12-OH
- Dodecaethylene glycol >=95% (oligomer purity)
- 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentat...
- CAS:
- 6790-09-6
- MF:
- C24H50O13
- MW:
- 546.65
- EINECS:
- 229-859-1
- Product Categories:
-
- Chemical Biology
- Chemical Synthesis
- High Oligomer Purity PEG
- PEGylation
- Ethylene Glycols
- Ethylene Glycols & Monofunctional Ethylene Glycols
- peg
- SiChem
- Mol File:
- 6790-09-6.mol
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Dodecaethylene glycol Chemical Properties
- Melting point:
- 38 °C
- Boiling point:
- 325 °C / 5mmHg
- Density
- 1.116±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- form
- wax
- pka
- 14.06±0.10(Predicted)
- color
- White to Orange to Green
- InChI
- InChI=1S/C24H50O13/c25-1-3-27-5-7-29-9-11-31-13-15-33-17-19-35-21-23-37-24-22-36-20-18-34-16-14-32-12-10-30-8-6-28-4-2-26/h25-26H,1-24H2
- InChIKey
- WRZXKWFJEFFURH-UHFFFAOYSA-N
- SMILES
- C(O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
- CAS DataBase Reference
- 6790-09-6
- EPA Substance Registry System
- Dodecaethylene glycol (6790-09-6)
MSDS
- Language:English Provider:SigmaAldrich
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Dodecaethylene glycol Usage And Synthesis
Description
PEG13 is a polymer consisting of ethylene glycol subunits with two terminal hydroxyl groups. The hydroxyl groups can undergo reactions to further derivatize the compound. The hydrophilic properties of the PEG linker increases the water solubility properties of attached compounds in aqueous media.
Uses
Dodecaethylene glycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Definition
ChEBI: Dodecaethylene glycol is a poly(ethylene glycol).
reaction suitability
reagent type: cross-linking reagent
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Dodecaethylene glycolSupplier
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd Gold
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