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HYDROQUININE

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HYDROQUININE Basic information

Product Name:
HYDROQUININE
Synonyms:
  • HYDROQUININE
  • Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (8alpha,9R)-
  • Quinine, 10,11-dihydro-
  • (8S,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol
  • (8α,9R)-10,11-Dihydro-6'-methoxycinchonan-9-ol
  • (8α,9R)-6'-Methoxy-10,11-dihydrocinchonan-9-ol
  • 10,11-Dihydroquinine
  • Hydroquinine,Dihydroquinine
CAS:
522-66-7
MF:
C20H26N2O2
MW:
326.44
EINECS:
208-334-0
Mol File:
522-66-7.mol
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HYDROQUININE Chemical Properties

Melting point:
168-176 °C(lit.)
alpha 
D18 -142° (alc); D20 -236° (c = 0.82 in 0.1N H2SO4)
Boiling point:
464.47°C (rough estimate)
Density 
1.1117 (rough estimate)
refractive index 
1.6800 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Ethanol (Sparingly), Methanol (Slightly)
form 
Solid
pka
5.33(at 25℃)
color 
White to Off-White
optical activity
[α]25/D 148°, c = 1 in ethanol
Water Solubility 
99.99mg/L(20 ºC)
Merck 
13,4832
BRN 
91444
InChIKey
LJOQGZACKSYWCH-WGFDLZGGSA-N
LogP
3.770 (est)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
1544
WGK Germany 
3
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29339900

MSDS

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HYDROQUININE Usage And Synthesis

Chemical Properties

Solid

Uses

(-)-Dihydroquinine, is a dihydro derivative of Quinine (Q694000), having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.

Definition

ChEBI: Hydroquinine is a cinchona alkaloid.

Purification Methods

Hydroquinine [522-66-7] M 326.4, m 168-171o, 171.5o, [ ] D-143o (c 1.087, EtOH), 5.33 and 8.87. Recrystallise hydroquinine from EtOH, Et2O or *C6H6. [Rabe & Schultz Chem Ber 66 120 1933, Beilstein 23 III/IV 3193, 23/13 V 340.]

HYDROQUININE Preparation Products And Raw materials

Preparation Products

(DHQ)2PYR

HYDROQUININESupplier

J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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jkinfo@jkchemical.com
Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006608290; 18621169109
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market03@meryer.com
BeiJing Hwrk Chemicals Limted
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0757-86329057 18934348241
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Energy Chemical
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021-021-58432009 400-005-6266
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sales8178@energy-chemical.com
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Email
sales@jingyan-chemical.com
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