3-Methyl-4-nitrophenol Chemical Properties

Melting point:

125-130 °C(lit.)

Boiling point:

200℃（decomposition）

Density 

1.2744 (estimate)

refractive index 

1.5744 (estimate)

Flash point:

110℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Sparingly)

form 

powder to crystal

pka

7.39±0.10(Predicted)

color 

Light yellow to Yellow to Orange

Water Solubility 

Soluble in water(1.34g/L).

BRN 

1868105

CAS DataBase Reference

2581-34-2(CAS DataBase Reference)

NIST Chemistry Reference

4-Nitro-5-methylphenol(2581-34-2)

EPA Substance Registry System

4-Nitro-m-cresol (2581-34-2)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-22

Safety Statements 

26-36/37-37/39-36-24/25

RIDADR 

UN 2446 6.1/PG 3

WGK Germany 

3

RTECS 

GP2625000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29089000

MSDS

• Language:English Provider:3-Methyl-4-nitrophenol
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

3-Methyl-4-nitrophenol Usage And Synthesis

Chemical Properties

YELLOWISH TO BEIGE CRYSTALLINE POWDER

Uses

3-Methyl-4-nitrophenol is a biochemical used in the preparation of phosphorothioamidate analogues as antimalarial agents. 3-methyl-4-nitrophenol has anti-androgenic activity. PNMC significantly inhibits basal and hCG-stimulated testosterone production in rats.

Production Methods

m-Cresol is nitrosated in isopropanol solution and the isolated 4-nitroso-m-cresol is treated with aqueous nitric acid to oxidize it to 3-Methyl-4-nitrophenol.

Definition

ChEBI: A C-nitro compound in which the nitro group is attached at C-4 of m-cresol.

3-Methyl-4-nitrophenol(2581-34-2)Related Product Information

• Acetonitrile
• Methylparaben
• Butylated Hydroxytoluene
• 2-Chloro-4-nitrophenol
• Methanol
• Sodium 3-nitrobenzenesulphonate
• Nitrophenol
• Methyl acetate
• 3-Nitroacetophenone
• Amylmetacresol
• 3-Fluoro-4-nitrophenol
• Methyl acrylate
• m-Cresol
• Cresol
• Kresoxim-methyl
• o-Cresol
• Basic Violet 1
• p-Cresol