Pyridinium tribromide Chemical Properties

Melting point:

127-133 °C

Density 

2.9569 (rough estimate)

refractive index 

1.6800 (estimate)

storage temp. 

Store at <= 20°C.

solubility 

soluble in Methanol

form 

Powder, Crystals and/or Chunks

color 

Red-orange to red to brown

Water Solubility 

decomposes

Sensitive 

Lachrymatory

Merck 

14,7973

BRN 

3690144

Stability:

Stable. Incompatible with strong oxidizing agents, strong bases.

InChIKey

YPCPFIMBGJOEKU-UHFFFAOYSA-O

CAS DataBase Reference

39416-48-3(CAS DataBase Reference)

EPA Substance Registry System

Pyridinium hydrogen tribromide (39416-48-3)

Safety Information

Hazard Codes 

C,Xi

Risk Statements 

37/38-34-36

Safety Statements 

26-36/37/39-45-24/25-27

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

3

Hazard Note 

Lachrymatory

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29333100

MSDS

• Language:English Provider:Pyridine hydrobromide compound with bromine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Pyridinium tribromide Usage And Synthesis

Chemical Properties

red crystals

Uses

Pyridine hydrobromide perbromide is used as a brominating reagent in alfa-bromination and alfa-thiocyanation of ketones, phenols, unsaturated and aromatic ethers. It is used as a raw material in the preparation of beta-adrenergic blocking agents. Furthermore, it is used as an analytical reagent.

Uses

Pyridinium Tribromide is a reagent used in the α-thiocyanation of ketones and has also been applied to the synthesis of β-adrenergic blocking agents (also known as β-blockers) for patients with heart failure.

Uses

In small-scale brominations, where it is much more convenient and agreeable to measure and use than elemental bromine.

Purification Methods

It is a very good brominating agent-liberating one mol of Br2. Purify it by recrystallisation from glacial acetic acid (33g from 100mL of AcOH) to give orange-red crystals. [Fieser & Fieser Reagents for Organic Chemistry 1 967 1967, Englert & McElvain J Am Chem Soc 51 865 1929, Beilstein 20 II 103, 20/5 V 181.]

Pyridinium tribromide(39416-48-3)Related Product Information

• Sodium bromate
• Boron tribromide
• Chromium picolinate
• Pyridine hydrobromide
• Pyridine hydrochloride
• Methyltriphenylphosphonium bromide
• Pyridinium chlorochromate
• Ethidium bromide
• Pyridine
• Phosphorus tribromide
• Pyridine sulfur trioxide
• Hydrogen bromide
• 2,4,6-Collidine
• Scopolamine hydrobromide
• Clidinium bromide
• DEXTROMETHORPHAN HYDROBROMIDE
• Bromine
• Methyl bromide