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MORPHINE SULFATE NARCOTIC ANALGESIC

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MORPHINE SULFATE NARCOTIC ANALGESIC Basic information

Product Name:
MORPHINE SULFATE NARCOTIC ANALGESIC
Synonyms:
  • Morphine sulfate salt pentahydrate,Morphine hemi[sulfate pentahydrate]
  • Morphine sulfate salt solution
  • MORPHINE SULFATE METHANOL SOLUTION
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, sulfate (2:1) (salt)
  • Avinza
  • Capros
  • Kapanol
  • Morphelan
CAS:
64-31-3
MF:
C18H25NO8S
MW:
415.458
EINECS:
200-582-8
Mol File:
64-31-3.mol
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MORPHINE SULFATE NARCOTIC ANALGESIC Chemical Properties

Melting point:
250 °C
Flash point:
11℃
storage temp. 
−20°C
CAS DataBase Reference
64-31-3
EPA Substance Registry System
Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-(5.alpha.,6.alpha.)-, sulfate (2:1) (64-31-3)
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Safety Information

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN 1230 3/PG 2
WGK Germany 
1
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MORPHINE SULFATE NARCOTIC ANALGESIC Usage And Synthesis

Originator

Avinza,Aetna Inc.

Uses

Analgesic (narcotic).

Definition

ChEBI: Morphine sulfate is an alkaloid sulfate salt. It contains a morphine.

Manufacturing Process

Morphin was extracted from the plant vegetable (the poppy) by the mixture of water and methanol or the aqueous solution of potassium pyrosulfate. The precipitation of the morphin was carried out by addition to the extract the aqueous solution of sodium carbonate.
Morphin can be obtained from the extract by using the cation exchanger.
Free base of morphin was transformated to the sulfate salt.

brand name

Astramorph (AstraZeneca); Avinza (Ligand); Depodur (Skyepharma); Duramorph (Baxter Healthcare); Infumorph (Baxter Healthcare); Kadian (Alpharma); Ms Contin (Purdue Frederick); Oramorph (Xanodyne).

Therapeutic Function

Narcotic analgesic, Sedative

Safety Profile

Poison by subcutaneous, intravenous, intraperitoneal, and intramuscular routes. Moderately toxic by ingestion and parenteral routes. An experimental teratogen. Experimental reproductive effects. Mutation data reported. Used as a narcotic. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and SOx.

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