TYROSINASE Chemical Properties

Melting point:

89-94 °C

storage temp. 

-20°C

form 

lyophilized powder

color 

Light brown to brown

biological source

fungus (mushroom)

Specific Activity

≥1000unit/mg solid

CAS DataBase Reference

9002-10-2

EPA Substance Registry System

Oxygenase, monophenol mono- (9002-10-2)

Safety Information

Hazard Codes 

Xn

Risk Statements 

42

Safety Statements 

22-24/25-45

WGK Germany 

2

F 

10-21

TYROSINASE Usage And Synthesis

Uses

Tyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.

General Description

Isoelectric point (pI): 4.7-5
pH optimum is 6-7

Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.

Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.

Biochem/physiol Actions

Converts tyrosine to L-DOPA or tyramine to dopamine

TYROSINASE(9002-10-2)Related Product Information

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• N-BUTYLISOCYANIDE
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