(+)-Bis[(R)-1-phenylethyl]amine Chemical Properties

Melting point:

~260 °C

Boiling point:

86 °C0.05 mm Hg(lit.)

alpha 

199 º (NEAT)

Density 

0.985 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.5523(lit.)

Flash point:

>230 °F

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

pka

8.79±0.29(Predicted)

optical activity

[α]20/D +199.0°, neat

Water Solubility 

Insoluble in water.

BRN 

3590931

CAS DataBase Reference

23294-41-9

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

3

(+)-Bis[(R)-1-phenylethyl]amine Usage And Synthesis

Uses

(+)-Bis[(R)-1-phenylethyl]amine play a very extensive role of making chirally optically active drugs and compounds. Also as intermediates.

Uses

(+)-Bis[(R)-1-phenylethyl]amine can be used:

• In the synthesis of?β-amino acids.
• In the preparation of chiral C(19)-C(26) and C(27)-C(32) moieties of scytophycin C.
• To induce enantioselectivity in the deprotonation of prochiral ketones.
• As a starting material for the synthesis of chiral phenolate ligands through Mannich condensation reaction.
• In the synthesis of chiral phosphoramidite ligands.
• To prepare chiral cyclic isoimidium salts, which are further used to synthesize chiral lactones through Diels-Alder reaction.

(+)-Bis[(R)-1-phenylethyl]amine(23294-41-9)Related Product Information

• Triethanolamine
• Triallylamine
• 2-(2-Aminoethylamino)ethanol
• Diethyltoluenediamine
• Bis(2-ethylhexyl)amine
• N,N-Diisopropylethylamine
• Triethylenediamine
• Diethylaminoethanol
• Triethylenetetramine
• Dibenzylamine
• (-)-Bis[(S)-1-phenylethyl]amine
• (+)-Bis[(R)-1-phenylethyl]amine