Tinoridine
Tinoridine Basic information
- Product Name:
- Tinoridine
- Synonyms:
-
- 2-amino-6-(phenylmethyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-ium-3-carboxylic acid ethyl ester
- 2-AMINO-3-ETHOXY-CARBONYL-6-BENZYL-4,5,6,7-TETRAHYDROTHIEN.
- Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
- tinoridine
- y-3642
- 2-amino-3-aethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridin
- 2-amino-3-ethoxycarbonyl-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine
- 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno(2,3-c)pyridine-3-carboxylicacidet
- CAS:
- 24237-54-5
- MF:
- C17H20N2O2S
- MW:
- 316.42
- EINECS:
- 246-102-0
- Mol File:
- 24237-54-5.mol
Tinoridine Chemical Properties
- Melting point:
- 112-113°C
- Boiling point:
- 493.5±45.0 °C(Predicted)
- Density
- 1.256±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly)
- form
- Solid
- pka
- 6.29±0.20(Predicted)
- color
- Light Yellow
Tinoridine Usage And Synthesis
Originator
Nonflamin,Yoshitomi,Japan,1971
Uses
Ethyl 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (Tinoridine) targets pantothenate synthetase which plays a significant role in the biosynthesis of pantothenate in Mycobacterium tuberculosis (MTB).
Definition
ChEBI: Tinoridine is a thienopyridine.
Manufacturing Process
A solution of 1-benzyl-4-piperidone, ethyl cyanoacetate, powdery sulfur and morpholine in ethanol is heated moderately under reflux for about 20 minutes to dissolve the powdery sulfur. The mixture is heated under reflux for one further hour to complete the reaction. On standing at room temperature, the mixture yields a precipitate. The precipitate is collected by filtration, washed well with methanol and recrystallized from methanol to give 2-amino-6- benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine as almost colorless needles melting at 112° to 113°C.
brand name
Tinoridine Hydrochloride is JAN.
Therapeutic Function
Antiinflammatory
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Tinoridine(24237-54-5)Related Product Information
- Benzyl benzoate
- Benzocaine
- Benzyl bromide
- 3-Aminopyridine
- Ethylparaben
- Pyridine
- Urethane
- RESMETHRIN
- ISOXADIFEN-ETHYL
- Benzyl alcohol
- Ethanol
- Ethyl acetate
- Tropisetron
- Tinoridine Hydrochloride,ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate monohydrochloride
- Tetrahydrothiophene
- ETHYL 2-AMINO-6-BENZOYL-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE
- Tinoridine
- 6-BENZYL-2-(2-CHLORO-PROPIONYLAMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID ETHYL ESTER HYDROCHLORIDE