Basic information Safety Supplier Related

2-CHLORO-4'-HYDROXYACETOPHENONE

Basic information Safety Supplier Related

2-CHLORO-4'-HYDROXYACETOPHENONE Basic information

Product Name:
2-CHLORO-4'-HYDROXYACETOPHENONE
Synonyms:
  • 4-hydroxyphenacylchloride
  • chlorophenacyle
  • p-(chloroacetyl)phenol
  • 2-Chloro-1-(4-hydroxy-phenyl)ethanone
  • Acetophenone, 2-chloro-4'-hydroxy-
  • Brn 2086326
  • Einecs 228-613-0
  • Ethanone, 2-chloro-1-(4-hydroxyphenyl)-
CAS:
6305-04-0
MF:
C8H7ClO2
MW:
170.59
EINECS:
228-613-0
Mol File:
6305-04-0.mol
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2-CHLORO-4'-HYDROXYACETOPHENONE Chemical Properties

Melting point:
145-146 °C
Boiling point:
241.44°C (rough estimate)
Density 
1.2315 (rough estimate)
refractive index 
1.5100 (estimate)
pka
7.72±0.15(Predicted)
CAS DataBase Reference
6305-04-0(CAS DataBase Reference)
EPA Substance Registry System
Ethanone, 2-chloro-1-(4-hydroxyphenyl)- (6305-04-0)
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Safety Information

HS Code 
2914790090
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2-CHLORO-4'-HYDROXYACETOPHENONE Usage And Synthesis

Uses

2-Chloro-1-(4-hydroxy-phenyl)-ethanone is a reagent that is used in the preparation of hydroxypyrimidine derivatives and their HDAC (histone deacetylases) inhibitory activity.

Preparation

Also obtained by reaction of acetyl chloride with anisole in the presence of aluminium chloride in n-heptane at 35° for 4 h 30 min (20%).

2-CHLORO-4'-HYDROXYACETOPHENONESupplier

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