2-CHLORO-4'-HYDROXYACETOPHENONE CAS#: 6305-04-0

2-CHLORO-4'-HYDROXYACETOPHENONE Basic information

Product Name:

2-CHLORO-4'-HYDROXYACETOPHENONE

Synonyms:

4-hydroxyphenacylchloride
chlorophenacyle
p-(chloroacetyl)phenol
2-Chloro-1-(4-hydroxy-phenyl)ethanone
Acetophenone, 2-chloro-4'-hydroxy-
Brn 2086326
Einecs 228-613-0
Ethanone, 2-chloro-1-(4-hydroxyphenyl)-

CAS:

6305-04-0

MF:

C8H7ClO2

MW:

170.59

EINECS:

228-613-0

Mol File:

6305-04-0.mol

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2-CHLORO-4'-HYDROXYACETOPHENONE Chemical Properties

Melting point:: 145-146 °C
Boiling point:: 241.44°C (rough estimate)
Density: 1.2315 (rough estimate)
refractive index: 1.5100 (estimate)
pka: 7.72±0.15(Predicted)
CAS DataBase Reference: 6305-04-0(CAS DataBase Reference)
EPA Substance Registry System: Ethanone, 2-chloro-1-(4-hydroxyphenyl)- (6305-04-0)

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Safety Information

HS Code: 2914790090

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2-CHLORO-4'-HYDROXYACETOPHENONE Usage And Synthesis

Uses

2-Chloro-1-(4-hydroxy-phenyl)-ethanone is a reagent that is used in the preparation of hydroxypyrimidine derivatives and their HDAC (histone deacetylases) inhibitory activity.

Preparation

Also obtained by reaction of acetyl chloride with anisole in the presence of aluminium chloride in n-heptane at 35° for 4 h 30 min (20%).

2-CHLORO-4'-HYDROXYACETOPHENONESupplier

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Shanghai Hanhong Scientific Co.,Ltd.

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Shandong Xiya Chemical Co., Ltd

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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