LODOXAMIDE
LODOXAMIDE Basic information
- Product Name:
- LODOXAMIDE
- Synonyms:
-
- LODOXAMIDE
- MW:
- 0
- Mol File:
- Mol File
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LODOXAMIDE Chemical Properties
- Melting point:
- >200°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly, Heated)
- form
- Solid
- color
- Off-White to Pale Orange
- Stability:
- Hygroscopic
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LODOXAMIDE Usage And Synthesis
Uses
Lodoxamide is an antiallergic drug that acts as a mast cell stabilizer. It is effective in the treatment of allergic conjunctivitis and in decreasing vascular permeability.
Clinical Use
Lodoxamide, which shows some structural similarities to cromolyn and nedocromil, also is a mast cell stabilizer that inhibits the immediate hypersensitivity reaction, preventing increases in vascular permeability associated with antigen-IgE–mediated responses. Its precise mechanism of action is not completely understood. It is used topically in the eye, principally for conjunctivitis and keratitis associated with vernal allergens.