Thalidomide-linker 13
Thalidomide-linker 13 Basic information
- Product Name:
- Thalidomide-linker 13
- Synonyms:
-
- Thalidomide-linker 13
- Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
- -oxyacetamide-PEG1-amine
- Thalidomide-O-amido-PEG1-NH2 hydrochloride
- N-(2-(2-Aminoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide hydrochloride
- Thalidomide-O-amido-PEG1-NH2.HCl
- Inhibitor,Thalidomide-O-amido-PEG-C-2-NH2 hydrochloride,ThalidomideOamidoPEGC2NH2 hydrochloride,inhibit,Thalidomide O amido PEG C2 NH2 hydrochloride,E3 Ligase Ligand-Linker Conjugates
- Thalidomide-O-C1-amido-PEG-C2-NH2 HCl
- CAS:
- 2204226-02-6
- MF:
- C19H23ClN4O7
- MW:
- 454.86
- Product Categories:
-
- peg
- Mol File:
- 2204226-02-6.mol
More
Less
Thalidomide-linker 13 Chemical Properties
- storage temp.
- 2-8°C, sealed storage, away from moisture
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
More
Less
Thalidomide-linker 13 Usage And Synthesis
Uses
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs[1].
IC 50
Cereblon
storage
Store at -20°C
References
[1] Chessum NEA, et al. Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766). J Med Chem. 2018 Feb 8;61(3):918-933. DOI:10.1021/acs.jmedchem.7b01406
Thalidomide-linker 13Supplier
Daicel Chiral Technologies (China)CO.,LTD
- Tel
- 021-50460086-9 15921403865
- han_yajun@dctc.daicel.com
Sichuan Wei Keqi Biological Technology Co., Ltd.
- Tel
- 028-81700200 18116577057
- 3003855609@qq.com
Shanghai EFE Biological Technology Co., Ltd.
- Tel
- 021-65675885 18964387627
- info@efebio.com
Shanghai YuanYe Biotechnology Co., Ltd.
- Tel
- 021-61312847; 18021002903
- 3008007409@qq.com
Aikon International Limited
- Tel
- 025-58859352 18068836627
- dt3@aikonchem.com
More
Less
Thalidomide-linker 13(2204226-02-6)Related Product Information
- Thalidomide-O-amido-C4-NH2 hydrochloride
- Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
- Thalidomide-O-amido-C8-NH2 hydrochloride
- Thalidomide-O-PEG4-Boc
- tert-butyl 3,3'-(2-aMino-2-((3-tert-butoxy-3-oxopropoxy)Methyl)propane-1,3-diyl)bis(oxy)dipropanoate
- E3 Ligase Ligand-Linker Conjugates 20
- Cereblon Ligand 1
- E3 Ligase Ligand-Linker Conjugates 21
- E3 Ligase Ligand-Linker Conjugates 19
- Thalidomide-O-PEG4-Propargyl
- Thalidomide-linker 10
- Thalidomide-O-amido-PEG4-azide
- Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
- N-(4-azidobutyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide
- Thalidomide-linker 15
- Thalidomide-linker 14
- E3 Ligase Ligand-Linker Conjugates 24 (TFA)
- Acetamide, N-(5-aminopentyl)-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-