9H-Carbazol-9-ol
9H-Carbazol-9-ol Basic information
- Product Name:
- 9H-Carbazol-9-ol
- Synonyms:
-
- 4 HYDROXY 9(H)CARBAZOLE
- 4-hydroxy carbonzole
- 4-hydroxy-9-(H)-Carbazol]
- 9H-Carbazol-9-ol
- 9H-Carbazole, 9-hydroxy-
- 9H-CARBAZOLE
- Carprofen Impurity 16 (Carprofen USP Related Compound A)
- CAS:
- 54989-33-2
- MF:
- C12H9NO
- MW:
- 183.21
- EINECS:
- 258-034-9
- Product Categories:
-
- Chemical intermediate for CARVEDILOL
- Mol File:
- 54989-33-2.mol
9H-Carbazol-9-ol Chemical Properties
- Melting point:
- 169-173 °C(lit.)
- Boiling point:
- 406.0±28.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 13.43±0.58(Predicted)
- InChI
- InChI=1S/C12H9NO/c14-13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)13/h1-8,14H
- InChIKey
- PWERSDAXNCUOIB-UHFFFAOYSA-N
- SMILES
- N1(O)C2=C(C=CC=C2)C2=C1C=CC=C2
- CAS DataBase Reference
- 54989-33-2(CAS DataBase Reference)
MSDS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
9H-Carbazol-9-ol Usage And Synthesis
Uses
9H-Carbazol-9-ol is a minor product converted from 9H-carbazole. 9H-Carbazole and its derivatives are of special pharmaceutical interest due to their versatile biological activities. 9H-Carbazole itself was found to be an inhibitor of angiogenesis and inflammation. Furthermore, 9H-carbazole is a basic structural element of a variety of naturally active and synthetic compounds with a broad range of action, showing antibacterial, antifungal, antiparasitic , antiviral, anticancer, adrenoceptor blocking , or protein-kinase inhibition activities[1].
References
[1] DOREEN WALDAU. Characterization of new oxidation products of 9H-carbazole and structure related compounds by biphenyl-utilizing bacteria[J]. Applied Microbiology and Biotechnology, 2009, 81 6: 1023-1031. DOI:10.1007/s00253-008-1723-8.
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