4-Bromomethyl-3-nitrobenzoic acid Chemical Properties

Melting point:

127-130 °C (lit.)

Boiling point:

392°C

Density 

1.814

refractive index 

1.6500 (estimate)

Flash point:

191°C

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

solubility 

DMF: soluble(lit.)

pka

3.42±0.10(Predicted)

Water Solubility 

Soluble in DMF and dichloromethane. Insoluble in water.

BRN 

1970939

CAS DataBase Reference

55715-03-2(CAS DataBase Reference)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45-25

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

19

HazardClass 

8

PackingGroup 

III

HS Code 

29163990

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

4-Bromomethyl-3-nitrobenzoic acid Usage And Synthesis

Chemical Properties

pale yellow to pink crystalline powder

Uses

Photolabile Nbb handle employed in solid-phase peptide synthesis:

Uses

4-Bromomethyl-3-nitrobenzoic acid is used as a reactant in the synthesis of 4-bromomethyl-3-nitrobenzoic acid succinimide ester, 4-((2-(hydroxymethyl)phenyl amino)methyl)-3-nitrobenzoic acid, 4-(2-hydroxyethylmercaptylmethyl)-3-nitrobenzoic acid. It is also used as a thiol photo-deprotection reagent, a starting material in the synthesis of 2H-indazole based library using parallel solution-phase methods.

General Description

4-Bromomethyl-3-nitrobenzoic acid (BNBA) is a benzoic acid derivative. It has been synthesized by the nitration of 4-bromomethylbenzoic acid using fuming nitric acid. It participates in the synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones.

4-Bromomethyl-3-nitrobenzoic acid(55715-03-2)Related Product Information

• 4-Nitrobenzoic acid
• 4-Bromomethylbenzoic acid
• 4-Bromobenzoic acid
• 3-Nitrobenzoic acid
• Methyl 2-bromobenzoate
• p-Toluic acid
• NITROGEN DIOXIDE
• 3-Bromonitrobenzene
• nitrotoluene
• 2-Nitrobenzyl bromide
• 4-Methylbenzyl bromide
• 4-(BROMOMETHYL)BENZALDEHYDE
• 2-(bromomethyl)-Benzenamine
• 4-Methyl-3-nitrobenzoic acid
• 4-METHYL-3-NITROBENZYL ALCOHOL
• Methyl 2-bromomethyl-5-nitrobenzoate
• 4-Bromomethyl-3-nitrobenzoic acid
• 4-bromomethyl-3-nitrobenzoic acid succinimide ester