heparinase I Chemical Properties

storage temp. 

-20°C

Safety Information

WGK Germany 

3

MSDS

• Language:English Provider:SigmaAldrich

heparinase I Usage And Synthesis

Uses

Heparinase I from Flavobacterium heparinum has been used:

• in the digestion of plasma samples
• to study the effect of medium, washing and sonication on the infectivity of Chlamydia pneumonia
• in enzymatic removal of heparan sulfate from the surface of human rhabdomyosarcoma cells

Biochem/physiol Actions

Heparinase I from Flavobacterium heparinum acts by cleaving the α-glycoside linkage at AT III binding site in heparin. This results in small oligosaccharide fragments and heparinase I neutralizes the protein′s action of anticoagulation. Therefore it might replace the use of protamine in reversing heparin induced anticoagulation after coronary artery bypass surgery. Heparinase I possesses a half-life of 15-18 minutes.

heparinase I(9025-39-2)Related Product Information

• SALCOMINE
• Tosylmethyl isocyanide
• COBALT(II) ACETYLACETONATE
• 2,4-PENTANEDIONE, SILVER DERIVATIVE
• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• PHENYLSELENOL
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
• METHYL ISOCYANOACETATE
• N-BUTYLISOCYANIDE
• 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
• Cupric acetylacetonate
• TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III)
• TERT-BUTYL ISOCYANIDE
• Aluminum acetylacetonate
• Tris(2,4-pentanedionato)chroMiuM(III)
• Benzyl isocyanide
• Ethyl isocyanoacetate
• HEPARINASE II,HEPARINASE III,heparinase ii from flavobacterium*heparinum