2-Chloro-6-fluorobenzoic acid Chemical Properties

Melting point:

155-157 °C(lit.)

Boiling point:

263.7±20.0 °C(Predicted)

Density 

1.4016 (estimate)

storage temp. 

Sealed in dry,Room Temperature

form 

powder to crystal

pka

2.04±0.10(Predicted)

color 

White to Gray to Brown

BRN 

973857

InChIKey

XNTIGDVFBDJLTQ-UHFFFAOYSA-N

CAS DataBase Reference

434-75-3(CAS DataBase Reference)

NIST Chemistry Reference

2-Chloro-6-fluorobenzoic acid(434-75-3)

Safety Information

Hazard Codes 

Xi,Xn

Risk Statements 

36/37/38-37/38-36-20/21/22

Safety Statements 

26-36-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29163900

MSDS

• Language:English Provider:2-Chloro-6-fluorobenzoic acid
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Chloro-6-fluorobenzoic acid Usage And Synthesis

Chemical Properties

White to light yellow crystal powder

Uses

2-Chloro-6-fluorobenzoic Acid is a versatile reactant used in the synthesis of biaryls via decarboxylative Pd-catalyzed cross-coupling with aryl iodides. Also used in the preparation of fluorinated biaryls and heterobiaryls using copper catalyzed decarboxylative cross-coupling of aryl and heteroalyl iodides or bromides with potassium polyfluorobenzoates.

General Description

2-Chloro-6-fluorobenzoic acid is a two-fold halogenated derivative of benzoic acid.

2-Chloro-6-fluorobenzoic acid(434-75-3)Related Product Information

• 2-Fluoro-6-Chlorobenzonitrile
• 4-Fluorobenzoic acid
• 3-Chloroperoxybenzoic acid
• Phenyl chlorothionocarbonate
• Benzyl chloroformate
• 2-Chloro-6-fluorophenol
• Allyl chloroformate
• (+)-MENTHYL CHLOROFORMATE
• Phenyl chloroformate
• Difluorochloromethane
• 2-CHLORO-3,6-DIFLUOROBENZOIC ACID
• 6-CHLORO-2-FLUORO-3-METHYLBENZOIC ACID
• t-butyl chloroformate
• Ethyl chloroformate
• 2-CHLORO-6-FLUORO-3-METHYLBENZOIC ACID
• 2,3,4,5-TETRAFLUORO-6-CHLOROBENZOIC ACID
• 2-CHLORO-6-FLUORO-3-METHOXYBENZOIC ACID
• Methyl chloroformate